Detalhe da pesquisa
1.
A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes.
Proc Natl Acad Sci U S A
; 121(26): e2405905121, 2024 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38889153
2.
HBO1 is required for the maintenance of leukaemia stem cells.
Nature
; 577(7789): 266-270, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827282
3.
Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation.
Nature
; 566(7745): 548-552, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30760924
4.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature
; 560(7717): 253-257, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30069049
5.
Synthesis of 3-Azabicyclo[3.1.0]hexane Derivates.
Chemistry
; 29(48): e202301017, 2023 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37269044
6.
Visible-Light-Induced Synthesis of 3-Alkyl Chromones under Catalyst- and Additive-Free Conditions.
J Org Chem
; 88(19): 13634-13644, 2023 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679947
7.
Photocatalytic Benzylic C-H Oxidation/Cyclization of Enaminones to the Synthesis of Polysubstituted Oxazoles.
J Org Chem
; 88(13): 8257-8267, 2023 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37262016
8.
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.
Biochem J
; 479(11): 1181-1204, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35552369
9.
Electrochemical Synthesis of Polysubstituted Sulfonated Pyrazoles via Cascade Intermolecular Condensation, Radical-Radical Cross Coupling Sulfonylation, and Pyrazole Annulation.
J Org Chem
; 87(19): 13138-13153, 2022 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36166815
10.
Crystal structure of the M5 muscarinic acetylcholine receptor.
Proc Natl Acad Sci U S A
; 116(51): 26001-26007, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31772027
11.
Stimulus-cleavable chemistry in the field of controlled drug delivery.
Chem Soc Rev
; 50(8): 4872-4931, 2021 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33734247
12.
The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Antimicrob Agents Chemother
; 65(11): e0031121, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34460304
13.
Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive.
Biol Reprod
; 103(2): 323-332, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32648904
14.
A Reusable CNT-Supported Single-Atom Iron Catalyst for the Highly Efficient Synthesis of C-N Bonds.
Chemistry
; 26(20): 4592-4598, 2020 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32053247
15.
I2-Promoted [4 + 2] cycloaddition of in situ generated azoalkenes with enaminones: facile and efficient synthesis of 1,4-dihydropyridazines and pyridazines.
Org Biomol Chem
; 18(46): 9483-9493, 2020 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33179698
16.
pH-Responsive Polymers for Improving the Signal-to-Noise Ratio of Hypoxia PET Imaging with [18 F]Fluoromisonidazole.
Macromol Rapid Commun
; 41(11): e2000061, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32250004
17.
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.
Nature
; 503(7475): 295-9, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121438
18.
1,2,4-Oxadiazole antimicrobials act synergistically with daptomycin and display rapid kill kinetics against MDR Enterococcus faecium.
J Antimicrob Chemother
; 73(6): 1562-1569, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29518208
19.
8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.
Chemistry
; 24(8): 1922-1930, 2018 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29171692
20.
Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
FASEB J
; 31(10): 4515-4532, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28687609