Detalhe da pesquisa
1.
Activating cryptic biosynthetic gene cluster through a CRISPR-Cas12a-mediated direct cloning approach.
Nucleic Acids Res
; 50(6): 3581-3592, 2022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35323947
2.
Crystallographic Deciphering of Spontaneous Self-Assembly of Achiral Calciphores to Chiral Complexes.
Chemistry
; 29(10): e202203127, 2023 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36408990
3.
Insights into specificity and catalytic mechanism of amphotericin B/nystatin thioesterase.
Proteins
; 89(5): 558-568, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33389775
4.
Efflux identification and engineering for ansamitocin P-3 production in Actinosynnema pretiosum.
Appl Microbiol Biotechnol
; 105(2): 695-706, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33394151
5.
Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin.
Molecules
; 26(22)2021 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34833880
6.
Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
Chembiochem
; 21(9): 1309-1314, 2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31777147
7.
A Hierarchical Network of Four Regulatory Genes Controlling Production of the Polyene Antibiotic Candicidin in Streptomyces sp. Strain FR-008.
Appl Environ Microbiol
; 86(9)2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086301
8.
Nonomuraea nitratireducens sp. nov., a new actinobacterium isolated from Suaeda australis Moq. rhizosphere.
Int J Syst Evol Microbiol
; 70(9): 5026-5031, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32790600
9.
Generation of tetramycin B derivative with improved pharmacological property based on pathway engineering.
Appl Microbiol Biotechnol
; 104(6): 2561-2573, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31989221
10.
Transcriptional regulation of a leucine-responsive regulatory protein for directly controlling lincomycin biosynthesis in Streptomyces lincolnensis.
Appl Microbiol Biotechnol
; 104(6): 2575-2587, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31993701
11.
p-Aminophenylalanine Involved in the Biosynthesis of Antitumor Dnacin B1 for Quinone Moiety Formation.
Molecules
; 25(18)2020 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32932689
12.
Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase.
Biochemistry
; 58(27): 2978-2986, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199122
13.
TetR-Type Regulator SLCG_2919 Is a Negative Regulator of Lincomycin Biosynthesis in Streptomyces lincolnensis.
Appl Environ Microbiol
; 85(1)2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30341075
14.
A3 foresight network on natural products.
J Ind Microbiol Biotechnol
; 46(3-4): 313-317, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30474768
15.
Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase.
Int J Mol Sci
; 20(4)2019 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30781619
16.
Reconstitution of Kinamycin Biosynthesis within the Heterologous Host Streptomyces albus J1074.
J Nat Prod
; 81(1): 72-77, 2018 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338229
17.
Enhanced lincomycin production by co-overexpression of metK1 and metK2 in Streptomyces lincolnensis.
J Ind Microbiol Biotechnol
; 45(5): 345-355, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29574602
18.
Corrections to: Enhanced lincomycin production by cooverexpression of metK1 and metK2 in Streptomyces lincolnensis.
J Ind Microbiol Biotechnol
; 45(6): 447-448, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29846840
19.
Mechanism of salinomycin overproduction in Streptomyces albus as revealed by comparative functional genomics.
Appl Microbiol Biotechnol
; 101(11): 4635-4644, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28401259
20.
Elimination of indigenous linear plasmids in Streptomyces hygroscopicus var. jinggangensis and Streptomyces sp. FR008 to increase validamycin A and candicidin productivities.
Appl Microbiol Biotechnol
; 101(10): 4247-4257, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238083