Detalhe da pesquisa
1.
Antiproliferative and apoptotic effects of the oxidative dimerization product of methyl caffeate on human breast cancer cells.
Bioorg Med Chem Lett
; 23(2): 574-8, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23228470
2.
Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity.
Bioorg Med Chem Lett
; 22(12): 3988-92, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22607675
3.
Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay.
Antiviral Res
; 204: 105364, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716929
4.
The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.
Cell Death Differ
; 29(2): 285-292, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34862481
5.
Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.
Eur J Med Chem
; 226: 113835, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509860
6.
Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.
ChemMedChem
; 16(18): 2823-2844, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34032019
7.
New 2-arylnaphthalenediols and triol inhibitors of HIV-1 integrase--discovery of a new polyhydroxylated antiviral agent.
Bioorg Med Chem
; 18(14): 5194-201, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20541944
8.
Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain.
Antiviral Res
; 162: 79-89, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30557576
9.
Reaction of rosmarinic acid with nitrite ions in acidic conditions: discovery of nitro- and dinitrorosmarinic acids as new anti-HIV-1 agents.
J Med Chem
; 51(8): 2575-9, 2008 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18351727
10.
Synthesis and antiviral properties of some polyphenols related to Salvia genus.
Bioorg Med Chem Lett
; 18(16): 4736-40, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18674899
11.
The total synthesis of fukiic acid, an HIV-1 integrase inhibitor.
Eur J Med Chem
; 43(10): 2268-71, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18243421
12.
Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones.
Eur J Med Chem
; 43(6): 1222-9, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17937972
13.
Targeting Transcriptional Enhanced Associate Domains (TEADs).
J Med Chem
; 61(12): 5057-5072, 2018 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29251924
14.
Toward the Discovery of a Novel Class of YAPâ»TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAPâ»TEAD Proteinâ»Protein Interface.
Cancers (Basel)
; 10(5)2018 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29738494
15.
Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.
ChemMedChem
; 12(12): 954-961, 2017 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334506
16.
Inhibition of hepatitis B virus replication by N-hydroxyisoquinolinediones and related polyoxygenated heterocycles.
Antiviral Res
; 143: 205-217, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450058
17.
Non-Photoinduced Biological Properties of Verteporfin.
Curr Med Chem
; 23(11): 1171-84, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26980565
18.
2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4.
Eur J Med Chem
; 117: 256-68, 2016 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27105029
19.
Anti-HIV activities of natural antioxidant caffeic acid derivatives: toward an antiviral supplementation diet.
Curr Med Chem
; 12(15): 1811-8, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16029149
20.
The preclinical discovery and development of dolutegravir for the treatment of HIV.
Expert Opin Drug Discov
; 10(11): 1243-53, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26517818