Detalhe da pesquisa
1.
Characterization of potential degradation products of brexpiprazole by liquid chromatography/quadrupole-time-of-flight mass spectrometry and nuclear magnetic resonance, and prediction of their physicochemical properties by ADMET Predictor™.
Rapid Commun Mass Spectrom
; 37(1): e9415, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36226712
2.
Exploration of the Plausible Mechanism of Ethambutol Induced Ocular Toxicity by Using Proteomics Informed Physiologically Based Pharmacokinetic (PBPK) Modeling.
Pharm Res
; 39(4): 677-689, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35301670
3.
Comparative Proteomics Analysis of the Postmitochondrial Supernatant Fraction of Human Lens-Free Whole Eye and Liver.
Drug Metab Dispos
; 49(7): 592-600, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33952609
4.
PBPK Analysis to Study the Impact of Genetic Polymorphism of NAT2 on Drug-Drug Interaction Potential of Isoniazid.
Pharm Res
; 38(9): 1485-1496, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34518943
5.
Successful Prediction of Fetal Exposure to Dual BCRP/P-gp Drug Substrates Using the Efflux Ratio-Relative Expression Factor Approach and PBPK M&S.
Clin Pharmacol Ther
; 115(5): 1044-1053, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38124355
6.
Successful Prediction of Human Hepatic Concentrations of Transported Drugs Using the Proteomics-Informed Relative Expression Factor Approach.
Clin Pharmacol Ther
; 115(3): 595-605, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38037845
7.
Predicting Human Fetal Drug Exposure Through Maternal-Fetal PBPK Modeling and In Vitro or Ex Vivo Studies.
J Clin Pharmacol
; 62 Suppl 1: S94-S114, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36106781
8.
Stress degradation study on entrectinib and characterization of its degradation products using HRMS and NMR.
J Pharm Biomed Anal
; 208: 114459, 2022 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34768159
9.
A Tribute to Professor Saranjit Singh - A Critical Thinker, Innovator, Mentor, and Educator.
J Pharm Sci
; 111(5): 1224-1231, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699842
10.
Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis.
J Pharm Biomed Anal
; 203: 114223, 2021 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34214766
11.
Characterization of stress degradation products of nintedanib by UPLC, UHPLC-Q-TOF/MS/MS and NMR: Evidence of a degradation product with a structure alert for mutagenicity.
J Pharm Biomed Anal
; 199: 114037, 2021 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33836462
12.
Characterization of degradation products of celiprolol hydrochloride using hyphenated mass and NMR techniques.
J Pharm Biomed Anal
; 197: 113953, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33618130
13.
Insights into the degradation chemistry of tazarotene, a third generation acetylenic retinoid: LC-HRMS (Orbitrap), LC-MSn and NMR characterization of its degradation products, and prediction of their physicochemical and ADMET properties.
J Pharm Biomed Anal
; 186: 113316, 2020 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413825
14.
Stability behaviour of antiretroviral drugs and their combinations. 11: Characterization of interaction products of zidovudine and efavirenz, and evaluation of their anti HIV-1 activity, and physiochemical and ADMET properties.
J Pharm Biomed Anal
; 178: 112911, 2020 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31627078
15.
In vitro evaluation of reactive nature of E- and Z-guggulsterones and their metabolites in human liver microsomes using UHPLC-Orbitrap mass spectrometer.
J Pharm Biomed Anal
; 186: 113275, 2020 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32247160
16.
Characterization of stable and reactive metabolites of piperine formed on incubation with human liver microsomes.
J Mass Spectrom
; 54(9): 738-749, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31368246
17.
A repository of protein abundance data of drug metabolizing enzymes and transporters for applications in physiologically based pharmacokinetic (PBPK) modelling and simulation.
Sci Rep
; 9(1): 9709, 2019 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31273226