Detalhe da pesquisa
1.
Neuroprotective and neurorestorative potential of propargylamine derivatives in ageing: focus on mitochondrial targets.
J Neural Transm (Vienna)
; 123(2): 125-35, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25859841
2.
Effects of novel neuroprotective and neurorestorative multifunctional drugs on iron chelation and glucose metabolism.
J Neural Transm (Vienna)
; 120(1): 37-48, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22446839
3.
Methacrylated fibrinogen hydrogels for 3D cell culture and delivery.
Acta Biomater
; 164: 94-110, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37030621
4.
Biomanufacturing Recombinantly Expressed Cripto-1 Protein in Anchorage-Dependent Mammalian Cells Growing in Suspension Bioreactors within a Three-Dimensional Hydrogel Microcarrier.
Gels
; 9(3)2023 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975692
5.
In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skipping antisense oligonucleotides.
Cell Death Dis
; 13(9): 779, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36085138
6.
Iron-chelating backbone coupled with monoamine oxidase inhibitory moiety as novel pluripotential therapeutic agents for Alzheimer's disease: a tribute to Moussa Youdim.
J Neural Transm (Vienna)
; 118(3): 479-92, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21360301
7.
The neuroprotective mechanism of 1-(R)-aminoindan, the major metabolite of the anti-parkinsonian drug rasagiline.
J Neurochem
; 112(5): 1131-7, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20002521
8.
Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration.
J Neurochem
; 113(2): 363-73, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20096090
9.
The novel multifunctional, iron-chelating drugs M30 and HLA20 protect pancreatic beta-cell lines from oxidative stress damage.
J Pharmacol Exp Ther
; 333(3): 874-82, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20237072
10.
The novel cholinesterase-monoamine oxidase inhibitor and antioxidant, ladostigil, confers neuroprotection in neuroblastoma cells and aged rats.
J Mol Neurosci
; 37(2): 135-45, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18751929
11.
Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents.
Prog Neurobiol
; 82(6): 348-60, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17659826
12.
The neuroprotective mechanism of action of the multimodal drug ladostigil.
Front Biosci
; 13: 5131-7, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18508575
13.
Physiological and pathological aspects of Abeta in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators.
BMC Neurosci
; 9 Suppl 2: S2, 2008 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19090990
14.
TVP1022 and propargylamine protect neonatal rat ventricular myocytes against doxorubicin-induced and serum starvation-induced cardiotoxicity.
J Cardiovasc Pharmacol
; 52(3): 268-77, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18806608
15.
The neuroprotective effect of ladostigil against hydrogen peroxide-mediated cytotoxicity.
Chem Biol Interact
; 175(1-3): 318-26, 2008 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18598687
16.
Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy.
Ann N Y Acad Sci
; 1122: 155-68, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18077571
17.
A multifunctional, neuroprotective drug, ladostigil (TV3326), regulates holo-APP translation and processing.
FASEB J
; 20(12): 2177-9, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16935943
18.
Novel multifunctional anti-Alzheimer drugs with various CNS neurotransmitter targets and neuroprotective moieties.
Curr Alzheimer Res
; 4(5): 522-36, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18220515
19.
The novel multitarget iron chelating and propargylamine drug M30 affects APP regulation and processing activities in Alzheimer's disease models.
Neuropharmacology
; 123: 359-367, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28571715
20.
A Novel Iron Chelator-Radical Scavenger Ameliorates Motor Dysfunction and Improves Life Span and Mitochondrial Biogenesis in SOD1G93A ALS Mice.
Neurotox Res
; 31(2): 230-244, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826939