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Relatively little is known about how social relationships affect later life planning. Our study focuses on an underexamined aspect of social relationships, frequency of contact - not only with family members but also with friends. Using data from a survey of Floridians aged 50 and older conducted between December 2020 and April 2021 (n = 3,832), we examine the association between frequency of contact and five planning types: finances, health care, living arrangements, driving retirement, and end-of-life. We found that more frequent contact was associated with greater likelihood of planning, and this result was largely consistent across types of relationships and types of planning. Our findings suggest that contact with family members and friends may encourage more planning, which could reduce the stress that can accompany later life transitions. Our study offers further evidence of social relationships' centrality to later life well-being and points to the many benefits of enhancing them.
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When Canadian broadcaster, Lisa LaFlamme, announced in August 2022 that CTV National News did not renew her contract, some observers suggested that the corporation's decision resulted from LaFlamme's choice to "let her hair go gray" during the pandemic. An international public outcry ensued on Twitter. Our study involved an examination of these tweets (n = 440). Analyses revealed that approximately 80 percent of tweets indicated opposition to LaFlamme's dismissal, while only 2 percent indicated support and 18 percent indicated a neutral position. Among tweets expressing opposition, the most common justification, found in 79 percent of these tweets, centered on assessments of the employer's decision as poor. The frequency of all other justifications for opposition was considerably lower, with only 26 percent of these tweets mentioning ageism, 22 percent mentioning sexism, and 20 percent mentioning a general sense of unfairness to LaFlamme. These findings suggest the salience of capitalist logics in shaping how the public frames gendered ageism in the workplace. Our analyses also suggest a view of responses to this inequality as personal bodywork choices. Together, these framings reflect a more individual- than structural-level critique of gendered ageism, knowledge of which can inform efforts to dismantle it.
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OBJECTIVE: To explore the attitudes, facilitators and barriers in providing oral care for inpatients with dysphagia post-stroke as perceived by healthcare professionals. BACKGROUND: Dysphagia is a common complication of stroke and is associated with a higher incidence of aspiration pneumonia, malnutrition and dehydration. In the acute phase of stroke recovery, a dental professional is not usually part of the multidisciplinary team caring for the patient and oral care is the responsibility of the healthcare professionals in the stroke unit. There is a lack of high-quality evidence to demonstrate the most effective method of providing oral care for patients with dysphagia post-stroke. MATERIALS AND METHODS: This was a single-site study conducted with healthcare professionals working in the Stroke Unit of Cork University Hospital in Ireland, using focus groups and a qualitative thematic analysis approach. RESULTS: A total of three focus groups were conducted in the Stroke Unit with 17 healthcare professionals. The focus groups included representation from all healthcare professional groups providing direct clinical care to patients on the Stroke Unit including geriatric medicine, dietetics, speech and language therapy, healthcare assistance, nursing, occupational therapy and physiotherapy. A qualitative thematic analysis was carried out and seven overarching themes emerged from the data. Three themes related to facilitators to providing oral care for this patient group: (i) a focus on oral care in both policy and practice, (ii) expanding professional roles in the provision of oral care, (iii) perceived importance of oral care in recovery and rehabilitation. Four themes related to barriers to the provision of oral care for this patient group: (i) lack of confidence and concerns related to the perceived risk for patients with dysphagia, (ii) unique challenges of patient and stroke-related factors, (iii) lack of resources and time and (iv) perceived importance of oral care in recovery and its relative importance with competing demands. CONCLUSION: Members of the stroke multidisciplinary team believe that they all have a part to play in the delivery of oral care for patients with dysphagia post-stroke. Opportunities exist for the development of multidisciplinary interventions to improve the oral cavity assessment and oral care provided in the Stroke Unit.
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Increasing numbers of women, of all ages, are choosing to travel alone - a trend accompanied by online articles providing advice to them. However, we are aware of only one study examining these articles, and it gave no attention to age. We conduct a content analysis of 75 online articles directed at solo women travelers, including 29 written for older women. Results revealed three themes - regulating risk, letting go, and discovering self. Their prevalence varied by articles' targeted age group, with those aimed at younger women focusing on solo travel's risks and those for older women highlighting its rewards.
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Comunicação , Internet , Viagem , Adulto , Fatores Etários , Idoso , Consumo de Bebidas Alcoólicas/epidemiologia , Feminino , Humanos , Fatores de Risco , Segurança , Autoimagem , Adulto JovemRESUMO
We used whole-genome sequencing (WGS) to delineate transmission networks and investigate the benefits of WGS during cluster investigation.We included clustered cases of multidrug-resistant (MDR) tuberculosis (TB)/extensively drug-resistant (XDR) TB linked by mycobacterial interspersed repetitive unit variable tandem repeat (MIRU-VNTR) strain typing or epidemiological information in the national cluster B1006, notified between 2007 and 2013 in the UK. We excluded from further investigation cases whose isolates differed by greater than 12 single nucleotide polymorphisms (SNPs). Data relating to patients' social networks were collected.27 cases were investigated and 22 had WGS, eight of which (36%) were excluded as their isolates differed by more than 12 SNPs to other cases. 18 cases were ruled into the transmission network based on genomic and epidemiological information. Evidence of transmission was inconclusive in seven out of 18 cases (39%) in the transmission network following WGS and epidemiological investigation.This investigation of a drug-resistant TB cluster illustrates the opportunities and limitations of WGS in understanding transmission in a setting with a high proportion of migrant cases. The use of WGS should be combined with classical epidemiological methods. However, not every cluster will be solvable, regardless of the quality of genomic data.
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Tuberculose Extensivamente Resistente a Medicamentos/epidemiologia , Polimorfismo de Nucleotídeo Único , Tuberculose Resistente a Múltiplos Medicamentos/epidemiologia , Sequenciamento Completo do Genoma , Técnicas de Tipagem Bacteriana , Análise por Conglomerados , Surtos de Doenças , Tuberculose Extensivamente Resistente a Medicamentos/transmissão , Humanos , Repetições Minissatélites , Mycobacterium tuberculosis/genética , Mycobacterium tuberculosis/isolamento & purificação , Tuberculose Resistente a Múltiplos Medicamentos/transmissão , Reino Unido/epidemiologiaRESUMO
LITAF (LPS-induced TNF-activating factor) is an endosome-associated integral membrane protein important for multivesicular body sorting. Several mutations in LITAF cause autosomal-dominant Charcot Marie Tooth disease type 1C. These mutations map to a highly conserved C-terminal region, termed the LITAF domain, which includes a 22 residue hydrophobic sequence and flanking cysteine-rich regions that contain peptide motifs found in zinc fingers. Although the LITAF domain is thought to be responsible for membrane integration, the membrane topology of LITAF has not been established. Here, we have investigated whether LITAF is a tail-anchored (TA) membrane-spanning protein or monotopic membrane protein. When translated in vitro, LITAF integrates poorly into ER-derived microsomes compared with Sec61ß, a bona fide TA protein. Furthermore, introduction of N-linked glycosylation reporters shows that neither the N-terminal nor C-terminal domains of LITAF translocate into the ER lumen. Expression in cells of an LITAF construct containing C-terminal glycosylation sites confirms that LITAF is not a TA protein in cells. Finally, an immunofluorescence-based latency assay showed that both the N- and C-termini of LITAF are exposed to the cytoplasm. Recombinant LITAF contains 1â mol/mol zinc, while mutation of predicted zinc-binding residues disrupts LITAF membrane association. Hence, we conclude that LITAF is a monotopic membrane protein whose membrane integration is stabilised by a zinc finger. The related human protein, CDIP1 (cell death involved p53 target 1), displays identical membrane topology, suggesting that this mode of membrane integration is conserved in LITAF family proteins.
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Proteínas de Transporte/química , Proteínas de Transporte/metabolismo , Doença de Charcot-Marie-Tooth/metabolismo , Proteínas de Membrana/química , Proteínas de Membrana/metabolismo , Proteínas Nucleares/química , Proteínas Nucleares/metabolismo , Fatores de Transcrição/química , Fatores de Transcrição/metabolismo , Motivos de Aminoácidos , Sequência de Aminoácidos , Proteínas Reguladoras de Apoptose/química , Proteínas Reguladoras de Apoptose/metabolismo , Linhagem Celular , Células HeLa , Humanos , Microssomos/metabolismo , Dados de Sequência Molecular , Transporte ProteicoRESUMO
The past few decades have seen increased scholarly attention to gay and lesbian individuals' aging experiences; however, few studies examine differences in subjective aging by sexual minority status. We identify four perspectives on the association between sexual minority status and subjective aging-double jeopardy, crisis competence, gender interactive, and limited salience perspectives. We examine each perspective's predictions using data from the first wave of Midlife in the United States (1995-1996; MIDUS). Ordinary least square regression models reveal strongest support for the limited salience perspective, suggesting that sexual minority status has weaker effects on subjective aging than do other social factors, such as age, health, and gender. However, some results provide support for the gender interactive perspective, positing that the effect of sexual minority status on subjective aging varies by gender. Our study provides an organizational framework of theoretical perspectives that can guide further examinations of variation in aging experiences by sexual minority status.
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Envelhecimento/psicologia , Conhecimentos, Atitudes e Prática em Saúde/etnologia , Minorias Sexuais e de Gênero/psicologia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estados Unidos/etnologiaRESUMO
Our study examines explanations for the "paradox" of older women's better emotional well-being compared with younger women. We consider the role of subjective experiences of aging in a society that devalues older women. Using a sample of women (n = 872) from the National Survey of Midlife Development in the United States (1995-1996 and 2004-2006), we examine the role of five components of the subjective experience of aging in explaining older women's better emotional well-being compared with younger women: age identity, conceptions of the timing of middle age, aging attitudes, aging anxieties, and self-assessed physiological changes. We find that, compared with women 50-54 years old, those 35-39 years old report lower positive affect, and those 25-49 report higher negative affect. These patterns are partially explained by younger women's greater anxiety about declines in health and attractiveness and older women's more youthful identities. Our study underscores the value of considering the implications of our ageist and sexist society for women's emotional well-being across adulthood.
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Envelhecimento/psicologia , Emoções , Autoimagem , Adulto , Idoso , Ansiedade/psicologia , Atitude , Feminino , Humanos , Pessoa de Meia-Idade , Estados UnidosRESUMO
Chordin-mediated regulation of bone morphogenetic protein (BMP) family growth factors is essential in early embryogenesis and adult homoeostasis. Chordin binds to BMPs through cysteine-rich von Willebrand factor type C (vWC) homology domains and blocks them from interacting with their cell surface receptors. These domains also self-associate and enable chordin to target related proteins to fine-tune BMP regulation. The chordin-BMP inhibitory complex is strengthened by the secreted glycoprotein twisted gastrulation (Tsg); however, inhibition is relieved by cleavage of chordin at two specific sites by tolloid family metalloproteases. As Tsg enhances this cleavage process, it serves a dual role as both promoter and inhibitor of BMP signalling. Recent developments in chordin research suggest that rather than simply being by-products, the cleavage fragments of chordin continue to play a role in BMP regulation. In particular, chordin cleavage at the C-terminus potentiates its anti-BMP activity in a type-specific manner.
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Receptores de Proteínas Morfogenéticas Ósseas/antagonistas & inibidores , Proteínas Morfogenéticas Ósseas/antagonistas & inibidores , Glicoproteínas/metabolismo , Peptídeos e Proteínas de Sinalização Intercelular/metabolismo , Modelos Biológicos , Proteínas/metabolismo , Transdução de Sinais , Metaloproteases Semelhantes a Toloide/metabolismo , Animais , Receptores de Proteínas Morfogenéticas Ósseas/agonistas , Receptores de Proteínas Morfogenéticas Ósseas/química , Receptores de Proteínas Morfogenéticas Ósseas/metabolismo , Proteínas Morfogenéticas Ósseas/química , Proteínas Morfogenéticas Ósseas/metabolismo , Glicoproteínas/química , Humanos , Peptídeos e Proteínas de Sinalização Intercelular/química , Fragmentos de Peptídeos/química , Fragmentos de Peptídeos/metabolismo , Domínios e Motivos de Interação entre Proteínas , Estabilidade Proteica , Proteínas/química , Proteólise , Metaloproteases Semelhantes a Toloide/químicaRESUMO
Geographic distribution records for the lone star tick [Amblyomma americanum (L.)] in the peer-reviewed literature are incomplete for Oklahoma, preventing accurate disease risk assessments. To address this issue and document the presence of A. americanum in available habitats throughout the state, county-scale tick records published in U.S. Department of Agriculture-Cooperative Economic Insect Reports and specimens maintained at the K.C. Emerson Entomology Museum, Oklahoma State University, were reviewed. In addition, dry ice traps and tick drags were used to collect adult and nymphal A. americanum from throughout the state. Review of published USDA reports and the local museum collection documented A. americanum in 49 total counties (35 and 35, respectively). Active surveillance efforts confirmed the presence of this tick in 50 counties from which this species had not been previously reported to be established, documenting A. americanum is established in 68 of the 77 (88.3%) counties in Oklahoma. Taken together, these data verify that A. americanum ticks are much more widespread in Oklahoma than reflected in the literature, a phenomenon likely repeated throughout the geographic range of this tick in the eastern half of North America.
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Ixodidae , Animais , Demografia , OklahomaRESUMO
Background and Objectives: Chronic pain, which affects more than 1 in 4 middle-aged and older adults, can have profound implications for everyday behaviors like driving. The literature examining it, however, is relatively small and is limited by its reliance on patient populations and its lack of attention to some driving-related behaviors and self-assessments that may signal the start of a transition from driving. Research Design and Methods: We address these issues using data from an online survey of Floridians aged 50 and older that was conducted between December 2020 and April 2021 and funded by the Florida Department of Transportation (n = 3,832). We ran multivariate regression analyses to examine the association between pain's interference with driving and 5 driving-related outcomes: self-rated driving ability, driving frequency, self-regulated driving, perceived nearness of driving retirement, and planning for driving retirement. Results: Results indicate that experiencing more pain that interferes with driving is associated with worse self-rated driving ability, more frequent self-regulated driving, and greater planning for driving retirement. It is not associated with driving frequency or with anticipating that driving retirement will occur in the next 5 years. Discussion and Implications: These findings indicate that greater pain may hasten the transition from driving, along with planning for it. These patterns suggest that pain may increase people's risk of isolation and other negative outcomes that can follow driving retirement; however, pain's effect on planning may reduce these risks. By focusing on transitioning from driving, our study reveals a largely overlooked benefit of reducing pain-It could extend people's years behind the wheel.
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BACKGROUND: Transmission of canine heartworm (Dirofilaria immitis) from infected to naïve dogs is dependent on successful mosquito feeding and survival. METHODS: To determine whether treating heartworm-infected dogs with fluralaner (Bravecto®) limits the survival of infected mosquitoes, and potentially the transmission of D. immitis, we allowed female mosquitoes to feed on microfilaremic dogs and evaluated mosquito survival and infection with D. immitis. Eight dogs were experimentally infected with D. immitis. On day 0 (~ 11 months post-infection), four microfilaremic dogs were treated with fluralaner according to label directions while the other four were non-treated controls. Mosquitoes (Aedes aegypti Liverpool) were allowed to feed on each dog on days -7, 2, 30, 56, and 84. Fed mosquitoes were collected, and the number of live mosquitoes determined at 6 h, 24 h, 48 h, and 72 h post-feeding. Surviving mosquitoes held for 2 weeks were dissected to confirm third-stage D. immitis larvae; PCR (12S rRNA gene) was performed post-dissection to identify D. immitis in mosquitoes. RESULTS: Prior to treatment, 98.4%, 85.1%, 60.7%, and 40.3% of mosquitoes fed on microfilaremic dogs were alive at 6 h, 24 h, 48 h, and 72 h post-feeding, respectively. Similarly, mosquitoes fed on microfilaremic, non-treated dogs were alive 6 h post-feeding (98.5-100%) throughout the study. In contrast, mosquitoes fed on fluralaner-treated dogs 2 days after treatment were dead or severely moribund by 6 h post-feeding. At 30 and 56 days post-treatment, > 99% of mosquitoes fed on treated dogs were dead by 24 h. At 84 days post-treatment, 98.4% of mosquitoes fed on treated dogs were dead by 24 h. Before treatment, third-stage larvae of D. immitis were recovered from 15.5% of Ae. aegypti 2 weeks after feeding, and 72.4% were positive for D. immitis by PCR. Similarly, 17.7% of mosquitoes fed on non-treated dogs had D. immitis third-stage larvae 2 weeks after feeding, and 88.2% were positive by PCR. Five mosquitoes fed on fluralaner-treated dogs survived 2 weeks post-feeding, and 4/5 were from day 84. None had third-stage larvae at dissection, and all were PCR-negative. CONCLUSION: The data indicate that fluralaner treatment of dogs kills mosquitoes and thus would be expected to reduce transmission of heartworm in the surrounding community.
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Aedes , Dirofilaria immitis , Dirofilariose , Doenças do Cão , Cães , Animais , Feminino , Dirofilaria immitis/genética , Dirofilariose/tratamento farmacológico , Mosquitos Vetores , Doenças do Cão/tratamento farmacológico , LarvaRESUMO
The expansion of life expectancy has precipitated a cultural transformation of the life course - altering the perceived temporal contours of middle and later life. However, our understanding of these perceptions is limited by the absence of a framework within which to examine them. This paper builds on the life course perspective - which emphasizes the objective patterning of lives - by focusing on the subjective side of the life course. Drawing on theoretically, methodologically, and substantively diverse studies, this paper develops the concept of the subjective life course - a term we use to denote individuals' perceptions of the life course, including its structure and timing and their advancing location in it. We outline two dimensions of the subjective life course - the target of the perception (i.e., generalized other versus self) and the temporal frame of reference (i.e., past, present, or future). Using the resulting framework as an organizational tool, we then discuss key constructs located at each intersection along these dimensions, providing examples, where possible, of empirical studies examining them. We close with a discussion of two broad directions for research: leveraging the framework to yield insight on the subjective life course and exploring links between objective and subjective dimensions of the life course.
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Geriatria , Acontecimentos que Mudam a Vida , Humanos , Envelhecimento , Sociologia , PrevisõesRESUMO
Medical sociology gives limited attention to age-a surprising observation given the aging of the population and the fact that age is among the strongest determinants of health. We examine this issue through an analysis of articles published in Journal of Health and Social Behavior (JHSB) and Sociology of Health & Illness (SHI) between 2000 and 2019. One in 10 articles focused on age or aging, with attention increasing over the period. However, the journals differed. More JHSB than SHI articles addressed it, but fewer focused on the latest life stages when frailty often appears. We discuss three dimensions of age that would enrich medical sociology: as a dimension of inequality akin to race and gender with similar health effects, as an institution interacting with the medical one, and as an identity-again, akin to race and gender-through which people process their experiences in ways that affect health.
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Sociologia Médica , Sociologia , Envelhecimento , Identidade de Gênero , Humanos , Comportamento SocialRESUMO
Due to an increase in bovine tuberculosis in cattle in the United Kingdom, we investigated the characteristics of Mycobacterium bovis infection in humans and assessed whether extensive transmission of M. bovis between humans has occurred. A cross-sectional study linking demographic, clinical, and DNA fingerprinting (using 15-locus mycobacterial interspersed repetitive-unit-variable-number tandem-repeat [MIRU-VNTR] typing) data on cases reported between 2005 and 2008 was undertaken. A total of 129 cases of M. bovis infection in humans were reported over the period, with a decrease in annual incidence from 0.065 to 0.047 cases per 100,000 persons. Most patients were born pre-1960, before widespread pasteurization was introduced (73%), were of white ethnicity (83%), and were born in the United Kingdom (76%). A total of 102 patients (79%) had MIRU-VNTR typing data. A total of 31 of 69 complete MIRU-VNTR profiles formed eight distinct clusters. The overall clustering proportion determined using the n - 1 method was 33%. The largest cluster, comprising 12 cases, was indistinguishable from a previously reported West Midlands outbreak strain cluster and included those cases. This cluster was heterogeneous, having characteristics supporting recent zoonotic and human-to-human transmission as well as reactivation of latent disease. Seven other, smaller clusters identified had demographics supporting recrudescence rather than recent infection. A total of 33 patients had incomplete MIRU-VNTR profiles, of which 11 may have yielded 2 to 6 further small clusters if typed to completion. The incidence of M. bovis in humans in the United Kingdom remains low, and the epidemiology is predominantly that of reactivated disease.
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Mycobacterium bovis/isolamento & purificação , Tuberculose/epidemiologia , Tuberculose/transmissão , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Técnicas de Tipagem Bacteriana , Análise por Conglomerados , Estudos Transversais , Impressões Digitais de DNA , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Epidemiologia Molecular , Tipagem Molecular , Tuberculose/microbiologia , Reino Unido/epidemiologia , Adulto JovemRESUMO
BACKGROUND AND OBJECTIVES: Grandparent-adult grandchild relationships may not be captured in existing grandparenting typologies, which focus on early stages of these relationships. Our study develops a typology for later stages, estimates the prevalence of grandparents in each category, and examines associations between category membership and grandparent and grandchild characteristics. RESEARCH DESIGN AND METHODS: Using a sample of 289 grandparents from the latest wave of the Longitudinal Study of Generations (2005), we employed latent class analysis to examine underlying categories of grandparent-adult grandchild relationships, based on four dimensions-frequency of contact, relationship quality, grandparents' receipt of support, and geographic distance. RESULTS: Three latent classes emerged: Geographically Distant/Low Contact (45%), Geographically Close/High Contact (42%), and Geographically Close/Low Contact (13%). While geographic distance and frequency of contact were dimensions distinguishing grandparent-adult grandchild relationships, receipt of support and relationship quality were not. Most grandparents reported close relationships but infrequent support. DISCUSSION AND IMPLICATIONS: By identifying categories of grandparent-adult grandchild relationships and factors influencing membership in them, our study may aid in efforts to strengthen those characterized by weak bonds-namely, those with grandparents who are older, frailer, and poorer.
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Fragilidade , Avós , Humanos , Relação entre Gerações , Análise de Classes Latentes , Estudos LongitudinaisRESUMO
OBJECTIVES: Popular responses to the pandemic illustrate ageism's pervasiveness and the extent of collective acquiescence to its newest expressions. We explore these themes by analyzing Twitter reactions to "calculated ageism"-a term we use to refer to a political figure's edict that older adults should sacrifice their lives if it will mitigate the pandemic's economic damage to younger people. METHOD: Using thematic analysis, we examine tweets (n = 188) responding to Texas Lt. Governor Dan Patrick's March 23, 2020, statement that encouraged generational self-sacrifice. Themes that emerged included positions of support or opposition and tweeters' critiques. RESULTS: The large majority of tweets-90%-opposed calculated ageism, while only 5% supported it and 5% conveyed no position. Opposition centered on moral critiques, political-economic critiques, assertions of older adults' worth, and public health arguments. Support centered on individual responsibility and patriotism. DISCUSSION: While prior research reveals ageism's entrenchment in popular culture, our study finds that it has limits and identifies the reasons underlying them. The most common reasons for opposing calculated ageism center on its immorality and on its privileging of the economic interests of the powerful few over the many, patterns suggesting that the boundaries of ageism are influenced by core beliefs about fairness. They also are shaped by a bedrock conviction that older lives have value. This intergenerational solidarity could be leveraged to reduce ageism during the pandemic and beyond.
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Etarismo/estatística & dados numéricos , Envelhecimento/psicologia , COVID-19/epidemiologia , Preconceito , Estereotipagem , Idoso , Etarismo/psicologia , Ansiedade/psicologia , COVID-19/psicologia , Feminino , Humanos , Masculino , Mudança Social , Identificação SocialRESUMO
Although social scientists have long assumed that intimate social relationships are more closely associated with women's than men's mental health, recent research indicates that there are no gender differences in the advantages of marriage and disadvantages of unmarried statuses when males' and females' distinct expressions of emotional distress are considered. These findings have led to the conclusion that there has been a convergence in the importance of intimate relationships for men's and women's mental health. However, these patterns may not be evident for nonmarital romantic relationships among current cohorts of young adults. In this article, we examine the associations among several dimensions of these relationships and symptoms of both depression and substance abuse/dependence in a diverse sample of young adults in Miami, Florida. We find gender differences that vary across dimensions of relationships: While current involvements and recent breakups are more closely associated with women's than men's mental health, support and strain in an ongoing relationship are more closely associated with men's than women's emotional well-being. Our findings highlight the need to consider the period in the life course as well as experiences of specific cohorts of men and women when theorizing about gender differences in the importance of intimate relationships for mental health.
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Corte/psicologia , Saúde Mental , Adolescente , Feminino , Florida , Humanos , Entrevistas como Assunto , Masculino , Modelos Teóricos , Estresse Psicológico , Inquéritos e Questionários , Adulto JovemRESUMO
OBJECTIVES: Although changes in body functioning and appearance signal the aging process to ourselves and others, studies give limited attention to the effect of bodily experiences of aging on age identity. Our study examines the effect on age identity of 3 categories of aging body reminders: everyday body problems, body repairs, and body aids. METHODS: Hierarchical linear models are run using 5 waves of the National Health and Aging Trends Study (2011-2015). Models predict the effect on age identity of change in the count of everyday body problems (e.g., pain), body repairs (i.e., surgeries and medications), and body aids (e.g., hearing aids). RESULTS: Increases in everyday body problems and body repairs (in particular, medications) predict older identities, with the strongest average effect found for everyday body problems. These results are observed in models controlling on health, suggesting that body reminders exert independent effects. DISCUSSION: Our study reveals a realm of aging experiences-bodily experiences-that influence age identity. Avenues for further research include examinations of other aging body reminders, as well as variation across individuals.
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Envelhecimento/psicologia , Imagem Corporal/psicologia , Nível de Saúde , Autoimagem , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Dor Crônica/psicologia , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Auxiliares Sensoriais/psicologia , Procedimentos Cirúrgicos Operatórios/psicologia , Estados UnidosRESUMO
BACKGROUND: Amblyomma americanum and Rhipicephalus sanguineus (sensu lato) nymphs commonly feed on and transmit pathogens to dogs (Canis familiaris). Control of immature and adult tick life stages is necessary to fully protect animals. We evaluated efficacy of oral fluralaner (Bravecto®) against induced infestations with A. americanum and R. sanguineus (s.l.) nymphs on dogs in two experiments. METHODS: In each experiment, 10 dogs were administered oral fluralaner chewable tablets one time on Day 0 at a targeted minimum dose of 25 mg/kg body weight and 10 dogs remained non-treated controls. Dogs were infested with two groups of 50 A. americanum nymphs and two groups of 50 R. sanguineus (s.l.) nymphs on Days -1, 6, 28, 56 and 84. At 48 h and 72 h post-infestation, nymphs were collected from dogs, assessed as live or dead, and enumerated into categories defining attachment and engorgement status. Fluralaner efficacy was determined in separate analyses against all live nymphs and against live-fed nymphs, i.e. live nymphs that were attached to dogs at the time of collection and/or were engorged. Fluralaner was considered effective when mean numbers of live ticks were reduced in fluralaner-treated dogs by ≥ 90%. RESULTS: Fluralaner efficacy against all live and live-fed A. americanum nymphs in the first experiment was > 94% on all collection days. Efficacy against all live R. sanguineus (s.l.) nymphs in the first experiment was > 96% on all collection days excluding the 48 h counts for infestations on Days 28 (83.7%), 56 (82.9%) and 84 (86.7%); efficacy against live-fed R. sanguineus (s.l.) nymphs was > 95% on all 48 h/72 h count days. Fluralaner efficacy against all live A. americanum nymphs in the second experiment was > 93% on all collection days for 8 weeks excluding the 48 h count for infestation on Day 56 (87.8%); efficacy against live-fed A. americanum nymphs was > 91% on all count days for 8 weeks. Efficacy against all live R. sanguineus (s.l.) nymphs in the second experiment was > 91% on all 72 h collection days except for infestations on Days 28 (76.8%) and 56 (86.3%); efficacy against live-fed R. sanguineus (s.l.) nymphs was 100% on all 72 h count days. CONCLUSIONS: A single administration of oral fluralaner to dogs is effective against A. americanum and R. sanguineus (s.l.) nymphs for up to 12 weeks.