Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.

Magkouta, Sophia; Veroutis, Dimitris; Pousias, Athanasios; Papaspyropoulos, Angelos; Pippa, Natassa; Lougiakis, Nikolaos; Kambas, Konstantinos; Lagopati, Nefeli; Polyzou, Aikaterini; Georgiou, Maria; Chountoulesi, Maria; Pispas, Stergios; Foutadakis, Spyros; Pouli, Nicole; Marakos, Panagiotis; Kotsinas, Athanassios; Verginis, Panayotis; Valakos, Dimitrios; Mizi, Athanasia; Papantonis, Argyris; Vatsellas, Giannis; Galanos, Panagiotis; Bartek, Jiri; Petty, Russell; Serrano, Manuel; Thanos, Dimitris; Roussos, Charis; Demaria, Marco; Evangelou, Konstantinos; Gorgoulis, Vassilis G.

Mol Cell ; 83(19): 3558-3573.e7, 2023 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-37802028

2.

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

Dietlein, Felix; Kalb, Bastian; Jokic, Mladen; Noll, Elisa M; Strong, Alexander; Tharun, Lars; Ozretic, Luka; Künstlinger, Helen; Kambartel, Kato; Randerath, Winfried J; Jüngst, Christian; Schmitt, Anna; Torgovnick, Alessandro; Richters, André; Rauh, Daniel; Siedek, Florian; Persigehl, Thorsten; Mauch, Cornelia; Bartkova, Jirina; Bradley, Allan; Sprick, Martin R; Trumpp, Andreas; Rad, Roland; Saur, Dieter; Bartek, Jiri; Wolf, Jürgen; Büttner, Reinhard; Thomas, Roman K; Reinhardt, H Christian.

Cell ; 162(1): 146-59, 2015 Jul 02.

Artigo em Inglês | MEDLINE | ID: mdl-26140595

3.

Golgi feels DNA's pain.

Foiani, Marco; Bartek, Jiri.

Cell ; 156(3): 392-3, 2014 Jan 30.

Artigo em Inglês | MEDLINE | ID: mdl-24485446

4.

ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.

Kumar, Amit; Mazzanti, Michele; Mistrik, Martin; Kosar, Martin; Beznoussenko, Galina V; Mironov, Alexandre A; Garrè, Massimiliano; Parazzoli, Dario; Shivashankar, G V; Scita, Giorgio; Bartek, Jiri; Foiani, Marco.

Cell ; 158(3): 633-46, 2014 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-25083873

5.

A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization.

Zampetidis, Christos P; Galanos, Panagiotis; Angelopoulou, Andriani; Zhu, Yajie; Polyzou, Aikaterini; Karamitros, Timokratis; Kotsinas, Athanassios; Lagopati, Nefeli; Mourkioti, Ioanna; Mirzazadeh, Reza; Polyzos, Alexandros; Garnerone, Silvano; Mizi, Athanasia; Gusmao, Eduardo G; Sofiadis, Konstantinos; Gál, Zita; Larsen, Dorthe H; Pefani, Dafni-Eleftheria; Demaria, Marco; Tsirigos, Aristotelis; Crosetto, Nicola; Maya-Mendoza, Apolinar; Papaspyropoulos, Angelos; Evangelou, Konstantinos; Bartek, Jiri; Papantonis, Argyris; Gorgoulis, Vassilis G.

Mol Cell ; 81(23): 4907-4923.e8, 2021 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-34793711

6.

Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps.

Paes Dias, Mariana; Tripathi, Vivek; van der Heijden, Ingrid; Cong, Ke; Manolika, Eleni-Maria; Bhin, Jinhyuk; Gogola, Ewa; Galanos, Panagiotis; Annunziato, Stefano; Lieftink, Cor; Andújar-Sánchez, Miguel; Chakrabarty, Sanjiban; Smith, Graeme C M; van de Ven, Marieke; Beijersbergen, Roderick L; Bartkova, Jirina; Rottenberg, Sven; Cantor, Sharon; Bartek, Jiri; Ray Chaudhuri, Arnab; Jonkers, Jos.

Mol Cell ; 81(22): 4692-4708.e9, 2021 11 18.

Artigo em Inglês | MEDLINE | ID: mdl-34555355

7.

ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

Toledo, Luis Ignacio; Altmeyer, Matthias; Rask, Maj-Britt; Lukas, Claudia; Larsen, Dorthe Helena; Povlsen, Lou Klitgaard; Bekker-Jensen, Simon; Mailand, Niels; Bartek, Jiri; Lukas, Jiri.

Cell ; 155(5): 1088-103, 2013 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-24267891

8.

Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.

Müller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar.

Mol Cell ; 77(5): 970-984.e7, 2020 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-31982308

9.

Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution.

Björkman, Andrea; Johansen, Søren L; Lin, Lin; Schertzer, Mike; Kanellis, Dimitris C; Katsori, Anna-Maria; Christensen, Søren T; Luo, Yonglun; Andersen, Jens S; Elsässer, Simon J; Londono-Vallejo, Arturo; Bartek, Jiri; Schou, Kenneth B.

Genes Dev ; 34(15-16): 1065-1074, 2020 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-32561545

10.

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.

Gudjonsson, Thorkell; Altmeyer, Matthias; Savic, Velibor; Toledo, Luis; Dinant, Christoffel; Grøfte, Merete; Bartkova, Jirina; Poulsen, Maria; Oka, Yasuyoshi; Bekker-Jensen, Simon; Mailand, Niels; Neumann, Beate; Heriche, Jean-Karim; Shearer, Robert; Saunders, Darren; Bartek, Jiri; Lukas, Jiri; Lukas, Claudia.

Cell ; 150(4): 697-709, 2012 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-22884692

11.

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.

Maiani, Emiliano; Milletti, Giacomo; Nazio, Francesca; Holdgaard, Søs Grønbæk; Bartkova, Jirina; Rizza, Salvatore; Cianfanelli, Valentina; Lorente, Mar; Simoneschi, Daniele; Di Marco, Miriam; D'Acunzo, Pasquale; Di Leo, Luca; Rasmussen, Rikke; Montagna, Costanza; Raciti, Marilena; De Stefanis, Cristiano; Gabicagogeascoa, Estibaliz; Rona, Gergely; Salvador, Nélida; Pupo, Emanuela; Merchut-Maya, Joanna Maria; Daniel, Colin J; Carinci, Marianna; Cesarini, Valeriana; O'sullivan, Alfie; Jeong, Yeon-Tae; Bordi, Matteo; Russo, Francesco; Campello, Silvia; Gallo, Angela; Filomeni, Giuseppe; Lanzetti, Letizia; Sears, Rosalie C; Hamerlik, Petra; Bartolazzi, Armando; Hynds, Robert E; Pearce, David R; Swanton, Charles; Pagano, Michele; Velasco, Guillermo; Papaleo, Elena; De Zio, Daniela; Maya-Mendoza, Apolinar; Locatelli, Franco; Bartek, Jiri; Cecconi, Francesco.

Nature ; 592(7856): 799-803, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33854232

12.

Tethered genes get checked during replication.

Lukas, Jiri; Bartek, Jiri.

Cell ; 146(2): 189-91, 2011 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-21784241

13.

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.

Lemmens, Bennie; Hegarat, Nadia; Akopyan, Karen; Sala-Gaston, Joan; Bartek, Jiri; Hochegger, Helfrid; Lindqvist, Arne.

Mol Cell ; 71(1): 117-128.e3, 2018 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-30008317

14.

Chromatin damage generated by DNA intercalators leads to degradation of RNA Polymerase II.

Espinoza, Jaime A; Kanellis, Dimitris C; Saproo, Sheetanshu; Leal, Karla; Martinez, Johana Fernandez; Bartek, Jiri; Lindström, Mikael S.

Nucleic Acids Res ; 52(8): 4151-4166, 2024 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-38340348

15.

A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors.

Corman, Alba; Kanellis, Dimitris C; Michalska, Patrycja; Häggblad, Maria; Lafarga, Vanesa; Bartek, Jiri; Carreras-Puigvert, Jordi; Fernandez-Capetillo, Oscar.

PLoS Biol ; 19(5): e3001263, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-34033645

16.

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Doil, Carsten; Mailand, Niels; Bekker-Jensen, Simon; Menard, Patrice; Larsen, Dorthe Helena; Pepperkok, Rainer; Ellenberg, Jan; Panier, Stephanie; Durocher, Daniel; Bartek, Jiri; Lukas, Jiri; Lukas, Claudia.

Cell ; 136(3): 435-46, 2009 Feb 06.

Artigo em Inglês | MEDLINE | ID: mdl-19203579

17.

High speed of fork progression induces DNA replication stress and genomic instability.

Maya-Mendoza, Apolinar; Moudry, Pavel; Merchut-Maya, Joanna Maria; Lee, MyungHee; Strauss, Robert; Bartek, Jiri.

Nature ; 559(7713): 279-284, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29950726

18.

Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway.

Maynard, Scott; Hall, Arnaldur; Galanos, Panagiotis; Rizza, Salvatore; Yamamoto, Tatsuro; Gram, Helena Hagner; Munk, Sebastian H N; Shoaib, Muhammad; Sørensen, Claus Storgaard; Bohr, Vilhelm A; Lerdrup, Mads; Maya-Mendoza, Apolinar; Bartek, Jiri.

Nucleic Acids Res ; 50(17): 9948-9965, 2022 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-36099415

19.

Long-term follow up of patients with WHO grade 2 oligodendroglioma.

Carstam, Louise; Latini, Francesco; Solheim, Ole; Bartek, Jiri; Pedersen, Lars K; Zetterling, Maria; Beniaminov, Stanislav; Sjåvik, Kristin; Ryttlefors, Mats; Jensdottir, Margret; Rydenhag, Bertil; Smits, Anja; Jakola, Asgeir S.

J Neurooncol ; 164(1): 65-74, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37603235

20.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

Skrott, Zdenek; Mistrik, Martin; Andersen, Klaus Kaae; Friis, Søren; Majera, Dusana; Gursky, Jan; Ozdian, Tomas; Bartkova, Jirina; Turi, Zsofia; Moudry, Pavel; Kraus, Marianne; Michalova, Martina; Vaclavkova, Jana; Dzubak, Petr; Vrobel, Ivo; Pouckova, Pavla; Sedlacek, Jindrich; Miklovicova, Andrea; Kutt, Anne; Li, Jing; Mattova, Jana; Driessen, Christoph; Dou, Q Ping; Olsen, Jørgen; Hajduch, Marian; Cvek, Boris; Deshaies, Raymond J; Bartek, Jiri.

Nature ; 552(7684): 194-199, 2017 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-29211715

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