What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? A survey and multi-stakeholder debate.

In the past decade, significant European calls for research proposals have supported translational collaborative research on non-communicable and infectious diseases within the biomedical life sciences by bringing together interdisciplinary and multinational consortia. This research has advanced our understanding of disease pathophysiology, marking considerable scientific progress. Yet, it is crucial to retrospectively evaluate these efforts' societal impact. Research proposals should be thoughtfully designed to ensure that the research findings can be effectively translated into actionable policies. In addition, the choice of scientific methods plays a pivotal role in shaping the societal impact of research discoveries. Understanding the factors responsible for current unmet public health issues and medical needs is crucial for crafting innovative strategies for research policy interventions. A multistakeholder survey and a roundtable helped identify potential needs for consideration in the EU research and policy agenda. Based on survey findings, mental health disorders, metabolic syndrome, cancer, antimicrobial resistance, environmental pollution, and cardiovascular diseases were considered the public health challenges deserving prioritisation. In addition, early diagnosis, primary prevention, the impact of environmental pollution on disease onset and personalised medicine approaches were the most selected unmet medical needs. Survey findings enabled the formulation of some research-policies interventions (RPIs), which were further discussed during a multistakeholder online roundtable. The discussion underscored recent EU-level activities aligned with the survey-derived RPIs and facilitated an exchange of perspectives on public health and biomedical research topics ripe for interdisciplinary collaboration and warranting attention within the EU's research and policy agenda. Actionable recommendations aimed at facilitating the translation of knowledge into transformative, science-based policies are also provided.

Tentativas de suicídio atendidas em um hospital de trauma em Curitiba-PR / Suicide attempts treated at a trauma hospital in Curitiba-PR

RESUMO Introdução: O objetivo do nosso estudo foi investigar os fatores epidemiológicos envolvidos nas tentativas de suicídio atendidas em um hospital de trauma em Curitiba-PR entre janeiro de 2014 a dezembro de 2017. Métodos: Trata-se de um estudo retrospectivo realizado com base na avaliação de fichas de notificação obrigatória e banco de dados do hospital. Foram incluídos pacientes atendidos por tentativas de suicídio, maiores de 18 anos atendidos num período de 48 meses. Foram analisados dados como sexo, idade, estado civil, meio de agressão, natureza da lesão, reincidência da tentativa e desfecho. 283 pacientes foram incluídos no estudo e analisados comparativamente ao perfil característico descrito na literatura. Resultados: Observou-se no período estudado um constante crescimento no número das tentativas, significativamente maior no sexo feminino. Apesar desse aumento em mulheres, houve predomínio de pacientes do sexo masculino 1,3:1 (p < 0,005). A idade média foi de 34,6 ± 13,25 anos e não apresentou diferença significativa entre os sexos. De modo geral, o principal meio utilizado foi objeto perfurocortante (32,8%), seguido por intoxicação (31,8%), homens utilizaram mais objetos cortantes e mulheres envenenamento. Do total de pacientes, 9 (3,2%) foram a óbito obtendo-se uma relação suicídios-tentativas de suicídio de 1:31. Conclusão: O perfil do paciente que tenta suicídio mudou em comparação a estudos anteriores. Embora o número de homens permaneça superior, o número de mulheres está crescendo. O aumento nos índices sugere que há necessidade de melhora das políticas públicas. PALAVRAS-CHAVE: Tentativa de suicídio, serviços médicos de emergência, centros de traumatologia

ABSTRACT Introduction: The aim of our study was to investigate the epidemiological factors involved in suicide attempts seen at a trauma hospital in Curitiba-PR between January 2014 and December 2017. Methods: This is a retrospective study based on the evaluation of hospital mandatory notification forms and database. Patients over 18 years of age who were seen for suicide attempts along a 48-month period were included. Data such as sex, age, marital status, means of aggression, nature of injury, recurrence of attempt, and outcome were analyzed. A total of 283 patients were included in the study and analyzed against the characteristic profile described in the literature. Results: During the study period, there was a constant increase in the number of attempts, significantly higher in females. Despite this increase in women, there was a predominance (1.3:1) of male patients (p < 0.005). The mean age was 34.6 ± 13.25 years and there was no significant gender difference. In general, the main means used was sharp objects (32.8%), followed by intoxication (31.8%), men used more sharp objects, while women, poisoning. Of the total number of patients, 9 (3.2%) died, with a suicides-attempts ratio of 1:31. Conclusion: The profile of the suicide attempt patient has changed compared to previous studies. While the number of men remains higher, the number of women is growing. The increase in indices suggests that public policies should be improved. KEYWORDS: Suicide attempt, emergency medical services, trauma centers