[Hot topics about early clinical trials at ASCO congress 2018: News pathways, new targets, new associations]. / Actualité des essais thérapeutiques précoces au congrès de l'ASCO 2018 : nouveaux mécanismes, nouvelles cibles, nouvelles associations.

Looking at the results of the early trials presented at the 2018 American Society of Clinical Oncology (ASCO) conference can help identify the molecules and strategies that will potentially enter the practices of tomorrow. It is in this spirit that this subject has justified the attention of residents in oncology and the writing of this synthesis. Molecules that can represent breakthrough innovations are presented as well as new therapeutics under development acting on targets already validated in clinical practice and early data of checkpoint inhibitors in combination with different immunomodulators, as well as new strategies for immunotherapies (vaccines and cell therapy).