Detalhe da pesquisa
1.
Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
Diabetologia
; 63(2): 395-409, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31796987
2.
Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.
Diabetologia
; 61(8): 1780-1793, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754287
3.
Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic ß Cells.
Cells
; 13(7)2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607078
4.
Endoplasmic reticulum stress mediates resistance to BCL-2 inhibitor in uveal melanoma cells.
Cell Death Discov
; 6: 22, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32337074
5.
Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances ß-cell function of obese Zucker rats.
Mol Metab
; 8: 23-36, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233519
6.
Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion.
Mol Metab
; 6(4): 340-351, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28377873
7.
Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes.
Expert Opin Ther Targets
; 19(8): 1037-50, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25814122
8.
Roles of Sphingolipid Metabolism in Pancreatic ß Cell Dysfunction Induced by Lipotoxicity.
J Clin Med
; 3(2): 646-62, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26237395