Detalhe da pesquisa
1.
Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies.
J Neural Transm (Vienna)
; 131(5): 525-561, 2024 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38554193
2.
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder.
Mol Psychiatry
; 27(11): 4662-4672, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36075963
3.
The GPR88 agonist RTI-13951-33 reduces alcohol drinking and seeking in mice.
Addict Biol
; 27(6): e13227, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36301207
4.
Ventral striatum regulates behavioral response to ethanol and MDMA combination.
Addict Biol
; 26(2): e12938, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666571
5.
Mu opioid receptors in GABAergic neurons of the forebrain promote alcohol reward and drinking.
Addict Biol
; 24(1): 28-39, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29094432
6.
Mammalian target of rapamycin complex 1 and its downstream effector collapsin response mediator protein-2 drive reinstatement of alcohol reward seeking.
Addict Biol
; 24(5): 908-920, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30022576
7.
Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome.
Proc Natl Acad Sci U S A
; 113(41): 11603-11608, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27671662
8.
Alcohol Elicits Functional and Structural Plasticity Selectively in Dopamine D1 Receptor-Expressing Neurons of the Dorsomedial Striatum.
J Neurosci
; 35(33): 11634-43, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26290240
9.
Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse.
Addict Biol
; 20(4): 629-42, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24801661
10.
Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors.
J Neurosci
; 33(36): 14369-78, 2013 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24005290
11.
Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
J Neurosci
; 32(43): 15124-32, 2012 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23100433
12.
The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors.
J Neurosci
; 32(45): 15849-58, 2012 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23136424
13.
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders.
Proc Natl Acad Sci U S A
; 107(46): 20093-8, 2010 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21041654
14.
Mu Opioid Receptor-Positive Neurons in the Dorsal Raphe Nucleus Are Impaired by Morphine Abstinence.
Biol Psychiatry
; 94(11): 852-862, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37393045
15.
Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation.
J Med Chem
; 66(4): 2964-2978, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749855
16.
Mu Opioid Receptor-Expressing Neurons in the Dorsal Raphe Nucleus Are Involved in Reward Processing and Affective Behaviors.
Biol Psychiatry
; 94(11): 842-851, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37285896
17.
Translational Structural and Functional Signatures of Chronic Alcohol Effects in Mice.
Biol Psychiatry
; 91(12): 1039-1050, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35654559
18.
Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system.
J Neurosci
; 30(43): 14502-12, 2010 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20980608
19.
Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.
J Med Chem
; 64(16): 12397-12413, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387471
20.
GPCR and Alcohol-Related Behaviors in Genetically Modified Mice.
Neurotherapeutics
; 17(1): 17-42, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31919661