Detalhe da pesquisa
1.
The Purinosome: A Case Study for a Mammalian Metabolon.
Annu Rev Biochem
; 91: 89-106, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320684
2.
From Bioorganic Models to Cells.
Annu Rev Biochem
; 90: 57-76, 2021 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34153218
3.
Metabolic channeling: predictions, deductions, and evidence.
Mol Cell
; 81(18): 3775-3785, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547238
4.
Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models.
Eur Heart J
; 44(14): 1265-1279, 2023 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36721994
5.
Human de novo purine biosynthesis.
Crit Rev Biochem Mol Biol
; 56(1): 1-16, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33179964
6.
Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling.
J Biol Chem
; 298(5): 101853, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331738
7.
Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90.
J Biol Chem
; 298(5): 101845, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35307352
8.
ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease.
Circulation
; 146(19): 1444-1460, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36073366
9.
A New View into the Regulation of Purine Metabolism: The Purinosome.
Trends Biochem Sci
; 42(2): 141-154, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28029518
10.
Hypoxia drives the assembly of the multienzyme purinosome complex.
J Biol Chem
; 295(28): 9551-9566, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32439803
11.
Microtubule-directed transport of purine metabolons drives their cytosolic transit to mitochondria.
Proc Natl Acad Sci U S A
; 115(51): 13009-13014, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30509995
12.
PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments.
Biochemistry
; 59(49): 4694-4702, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242956
13.
Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen.
J Biol Chem
; 294(13): 5157-5168, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700555
14.
RNA primer-primase complexes serve as the signal for polymerase recycling and Okazaki fragment initiation in T4 phage DNA replication.
Proc Natl Acad Sci U S A
; 114(22): 5635-5640, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28507156
15.
Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation.
J Proteome Res
; 18(5): 2078-2087, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30964683
16.
Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same Obstacle.
Chem Rev
; 117(12): 7857-7877, 2017 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28497687
17.
Stability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesis.
Proc Natl Acad Sci U S A
; 113(13): E1777-86, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26976599
18.
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis.
Biochemistry
; 57(23): 3217-3221, 2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29553718
19.
Understanding DNA replication by the bacteriophage T4 replisome.
J Biol Chem
; 292(45): 18434-18442, 2017 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972188
20.
Expression of the purine biosynthetic enzyme phosphoribosyl formylglycinamidine synthase in neurons.
J Neurochem
; 144(6): 723-735, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29337348