Detalhe da pesquisa
1.
Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions.
Neurobiol Dis
; 191: 106411, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228253
2.
Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction.
BMC Vet Res
; 16(1): 356, 2020 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32977825
3.
TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson's disease.
Proc Natl Acad Sci U S A
; 114(40): 10773-10778, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923922
4.
Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Neurobiol Dis
; 112: 106-118, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29341898
5.
The contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's disease.
J Neurochem
; 137(3): 331-59, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26852372
6.
Targeted gene delivery to the enteric nervous system using AAV: a comparison across serotypes and capsid mutants.
Mol Ther
; 23(3): 488-500, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25592336
7.
Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse.
Front Aging Neurosci
; 15: 1265151, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37842124
8.
Basic Concepts in Viral Vector-Mediated Gene Therapy.
Methods Mol Biol
; 1937: 3-26, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30706387
9.
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.
Acta Neuropathol Commun
; 7(1): 8, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30646956
10.
Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity.
Front Mol Neurosci
; 11: 36, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29497361
11.
Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease.
Nat Struct Mol Biol
; 24(8): 632-642, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671665
12.
Intraparenchymal Stereotaxic Delivery of rAAV and Special Considerations in Vector Handling.
Methods Mol Biol
; 1382: 199-215, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611588
13.
Gene Therapy of the Peripheral Nervous System: The Enteric Nervous System.
Methods Mol Biol
; 1382: 263-74, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611593
14.
Lentivirus Production and Purification.
Methods Mol Biol
; 1382: 107-14, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611582
15.
Continuous Collection of Adeno-Associated Virus from Producer Cell Medium Significantly Increases Total Viral Yield.
Hum Gene Ther Methods
; 27(1): 32-45, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26863210
16.
Impact of age and vector construct on striatal and nigral transgene expression.
Mol Ther Methods Clin Dev
; 3: 16082, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933309
17.
The role of parkin in the differential susceptibility of tuberoinfundibular and nigrostriatal dopamine neurons to acute toxicant exposure.
Neurotoxicology
; 46: 1-11, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25447324