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1.
Ann ICRP ; 48(2-3): 9-501, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31850780

RESUMO

The 2007 Recommendations (ICRP, 2007) introduced changes that affect the calculation of effective dose, and implied a revision of the dose coefficients for internal exposure, published previously in the Publication 30 series (ICRP, 1979a,b, 1980a, 1981, 1988) and Publication 68 (ICRP, 1994b). In addition, new data are now available that support an update of the radionuclide-specific information given in Publications 54 and 78 (ICRP, 1989a, 1997) for the design of monitoring programmes and retrospective assessment of occupational internal doses. Provision of new biokinetic models, dose coefficients, monitoring methods, and bioassay data was performed by Committee 2 and its task groups. A new series, the Occupational Intakes of Radionuclides (OIR) series, will replace the Publication 30 series and Publications 54, 68, and 78. OIR Part 1 (ICRP, 2015) describes the assessment of internal occupational exposure to radionuclides, biokinetic and dosimetric models, methods of individual and workplace monitoring, and general aspects of retrospective dose assessment. OIR Part 2 (ICRP, 2016), OIR Part 3 (ICRP, 2017), this current publication, and the final publication in the OIR series (OIR Part 5) provide data on individual elements and their radioisotopes, including information on chemical forms encountered in the workplace; a list of principal radioisotopes and their physical half-lives and decay modes; the parameter values of the reference biokinetic models; and data on monitoring techniques for the radioisotopes most commonly encountered in workplaces. Reviews of data on inhalation, ingestion, and systemic biokinetics are also provided for most of the elements. Dosimetric data provided in the printed publications of the OIR series include tables of committed effective dose per intake (Sv per Bq intake) for inhalation and ingestion, tables of committed effective dose per content (Sv per Bq measurement) for inhalation, and graphs of retention and excretion data per Bq intake for inhalation. These data are provided for all absorption types and for the most common isotope(s) of each element. The online electronic files that accompany the OIR series of publications contains a comprehensive set of committed effective and equivalent dose coefficients, committed effective dose per content functions, and reference bioassay functions. Data are provided for inhalation, ingestion, and direct input to blood. This fourth publication in the OIR series provides the above data for the following elements: lanthanum (La), cerium (Ce), praseodymium (Pr), neodymium (Nd), promethium (Pm), samarium (Sm), europium (Eu), gadolinium (Gd), terbium (Tb), dysprosium (Dy), holmium (Ho), erbium (Er), thulium (Tm), ytterbium (Yb), lutetium (Lu), actinium (Ac), protactinium (Pa), neptunium (Np), plutonium (Pu), americium (Am), curium (Cm), berkelium (Bk), californium (Cf), einsteinium (Es), and fermium (Fm).


Assuntos
Exposição Ocupacional/prevenção & controle , Exposição à Radiação/prevenção & controle , Monitoramento de Radiação/normas , Proteção Radiológica/normas , Radioisótopos/efeitos adversos , Relação Dose-Resposta à Radiação , Humanos , Exposição à Radiação/normas , Radiação Ionizante , Medição de Risco
2.
Probl Radiac Med Radiobiol ; 23: 37-48, 2018 Dec.
Artigo em Inglês, Ucraniano | MEDLINE | ID: mdl-30582835

RESUMO

Nuclear installations may contain a large inventory of radioactive material and an emergency caused by an accident, natural disaster, or malevolent act may cause uncontrolled releases of radionuclides to the environment. The paper presents a brief overview of individual radiological monitoring in case of major releases of radionuclides to the environment and introduces the new Report 92 of the International Commission on Radiation Units and Measurements (ICRU) on Radiation Monitoring for Protection of the Public after Major Releases of Radionuclides to the Environment. The Report was prepared taking into account the results of the research «Development of the program for radiation and hygienic monitoring for the radiological protection of human under radiation accidents and acts of nuclear terrorism¼ which was carried out in the internal dosimetry laboratory of the NRCRM of NAMS of Ukraine in 2016-2018. The Report Committee was headed by the scientific supervisor of the research, the Committee consisted of leading experts from UK, Italy, China, Germany, Russia, Slovenia, United States, Ukraine, Japan, and experts from the International Atomic Energy Agency. The preparation of the Report was supported by the US Environmental Protection Agency, US Nuclear Regulatory Commission, US Department of Energy, National Academy of Medical Sciences of Ukraine, and Radiation Protection Institute of the ATS of Ukraine.


Assuntos
Defesa Civil/organização & administração , Planejamento em Desastres/organização & administração , Lesões por Radiação/prevenção & controle , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Humanos , Cooperação Internacional , Centrais Nucleares , Lesões por Radiação/diagnóstico , Lesões por Radiação/patologia , Lesões por Radiação/terapia , Monitoramento de Radiação/instrumentação , Proteção Radiológica/instrumentação , Liberação Nociva de Radioativos/classificação , Radioisótopos/análise , Radiologia/métodos , Relatório de Pesquisa , Ucrânia
3.
Radiat Prot Dosimetry ; 125(1-4): 205-8, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17578871

RESUMO

The 'Individual Monitoring for Internal Exposure' (IMIE) computer codes are the family of interactive tools for interpretation of the bioassay data and individual dose assessments. During 10 y of the IMIE evolution, the extensive experience in the IMIE application has been accumulated and the underlying methodology has undergone essential improvements. The main distinguished feature of the IMIE ideology is the automated numerical analysis of all examined exposure scenarios with the succeeding interactive identification of events of intake(s) and assessment of associated doses. The numerical deconvolution algorithms and the massive library of tabulated 'bioassay/dose response functions' are employed for the processing of an arbitrary pattern of intake and complex exposure conditions. This article discusses details implemented in the IMIE algorithms and examples of IMIE application.


Assuntos
Bioensaio/métodos , Modelos Biológicos , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Software , Interface Usuário-Computador , Algoritmos , Carga Corporal (Radioterapia) , Simulação por Computador , Humanos , Internacionalidade , Eficiência Biológica Relativa , Reprodutibilidade dos Testes , Medição de Risco/métodos , Sensibilidade e Especificidade , Design de Software
4.
Radiat Prot Dosimetry ; 125(1-4): 520-2, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17012307

RESUMO

In the scope of the IDEAS project to develop General Guidelines for the Assessment of Internal Dose from Monitoring data, two databases were compiled. The IDEAS Bibliography database contains references dealing with problems related to cases of internal contamination. The IDEAS Internal Contamination Database now contains more than 200 cases of internal contamination. In the near future, the IDEAS Internal Contamination database will be made available to the internal dosimetry community. The database has several potential applications, including: training, testing biokinetic models, testing software for calculating intakes and doses from bioassay data, comparison of data from a new accidental intake with that from previous exposures to similar materials. The database is by no means complete, and this presentation is also an appeal for internal contamination cases to extend and update it.


Assuntos
Bioensaio/métodos , Bases de Dados Factuais , Exposição Ambiental/análise , Modelos Biológicos , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Radioisótopos/farmacocinética , Simulação por Computador , Humanos , Internacionalidade , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
5.
Radiat Prot Dosimetry ; 125(1-4): 19-22, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17041240

RESUMO

In recent major international intercomparison exercises on intake and internal dose assessments from monitoring data, the results calculated by different participants varied significantly. Based on this experience the need for harmonisation of the procedures has been formulated within an EU 5th Framework Programme research project. The aim of the project, IDEAS, is to develop general guidelines for standardising assessments of intakes and internal doses. The IDEAS project started in October 2001 and ended in June 2005. The project is closely related to some goals of the work of Committee 2 of the ICRP and since 2003 there has been close cooperation between the two groups. To ensure that the guidelines are applicable to a wide range of practical situations, the first step was to compile a database of well-documented cases of internal contamination. In parallel, an improved version of an existing software package was developed and distributed to the partners for further use. A large number of cases from the database was evaluated independently by the partners and the results reviewed. Based on these evaluations, guidelines were drafted and discussed with dosimetry professionals from around the world by means of a virtual workshop on the Internet early in 2004. The guidelines have been revised and refined on the basis of the experiences and discussions in this virtual workshop. The general philosophy of the Guidelines is presented here, focusing on the principles of harmonisation, optimisation and proportionality. Finally, the proposed Levels of Task to structure the approach of internal dose evaluation are reported.


Assuntos
Fidelidade a Diretrizes/normas , Guias como Assunto , Modelos Biológicos , Exposição Ocupacional/análise , Monitoramento de Radiação/normas , Proteção Radiológica/normas , Gestão da Segurança/normas , Algoritmos , Simulação por Computador , Europa (Continente) , Humanos , Exposição Ocupacional/prevenção & controle , Padrões de Referência , Eficiência Biológica Relativa , Medição de Risco/normas
6.
Radiat Prot Dosimetry ; 127(1-4): 303-10, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17933785

RESUMO

The need for harmonisation of the procedures for internal dose assessment has been recognised within an EU research project under the 5th Framework Programme. The aim of the IDEAS project was to develop general guidelines for standardising assessments of intakes and internal doses. It started in October 2001 and ended in June 2005. The project is closely related to some goals of the work of Committee 2 of the International Commission on Radiological Protection and since 2003 there has been close co-operation between the two groups. The general philosophy of the guidelines is focusing on the principles of harmonisation, accuracy and proportionality. The proposed system of 'level of task' to structure the approach of internal dose evaluation is also reported. Some details of the internal structure of the guidelines for the different pathways of intake are provided.


Assuntos
Algoritmos , Bioensaio/métodos , Modelos Biológicos , Guias de Prática Clínica como Assunto , Radiometria/métodos , Simulação por Computador , União Europeia , Humanos , Doses de Radiação , Eficiência Biológica Relativa
7.
Radiat Prot Dosimetry ; 127(1-4): 93-6, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17556343

RESUMO

The objective of this Task Group is the coordination of research studies on biokinetic models and the evaluation of the implications of new biokinetic models on dose assessment and safety standards. For this the new ICRP models, which will be used for a revision of ICRP Publications 30, 54, 68 and 78, are implemented into six different computer codes in five European countries and quality assured by intercomparison procedures. The work has started with the implementation of the new ICRP Alimentary Tract Model. New systemic models and the new NCRP wound model will follow. The work also includes the evaluation of experimental results in terms of formulation by the new model structures and a quality assurance of model formulation.


Assuntos
Corpos Estranhos/fisiopatologia , Modelos Biológicos , Lesões por Radiação/fisiopatologia , Radioisótopos/farmacocinética , Radioisótopos/toxicidade , Radiometria/métodos , Ferimentos Penetrantes/fisiopatologia , Carga Corporal (Radioterapia) , Simulação por Computador , Corpos Estranhos/complicações , Humanos , Cinética , Taxa de Depuração Metabólica , Lesões por Radiação/etiologia , Eficiência Biológica Relativa , Ferimentos Penetrantes/etiologia
8.
Radiat Prot Dosimetry ; 127(1-4): 321-4, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17686964

RESUMO

The paper discusses the system of individual monitoring for internal exposure, deployed by the Ukrainian Radiation Protection Institute as an integral component of the Shelter Implementation Plan (SIP) at the Chornobyl industrial site. SIP anticipates involving of up to 10,00 workers of numerous SIP contractors. A typical daily shift comprises several hundred workers. Most of them have a direct contact with the irradiated nuclear fuel, fuel-contained aerosols and other contaminated materials on the industrial site. The hierarchical SIP individual monitoring program has been designed with consideration of peculiarities of SIP exposure conditions and aims at the timely and reliable identification of intakes, assessment of doses and initiation of measures for prevention of further intakes.


Assuntos
Acidente Nuclear de Chernobyl , Exposição Ambiental/análise , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Liberação Nociva de Radioativos/prevenção & controle , Gestão da Segurança/métodos , Gestão da Segurança/organização & administração , Bioensaio , Federação Russa
9.
Radiat Prot Dosimetry ; 127(1-4): 317-20, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17562645

RESUMO

As part of the EU Fifth Framework Programme IDEAS project 'General Guidelines for the Evaluation of Incorporation Monitoring Data', and in collaboration with the International Atomic Energy Agency, a new intercomparison exercise for the assessment of doses from intakes of radionuclides was organised. Several cases were selected, to cover a wide range of practices in the nuclear fuel cycle and medical applications. The cases were: (1) acute intake of HTO, (2) acute inhalation of the fission products 137Cs and 90Sr, (3) acute inhalation of 60Co, (4) repeated intakes of 131I, (5) intake of enriched uranium and (6) single intake of Pu isotopes and 241Am. This intercomparison exercise especially focused on the effect of the Guidelines proposed by the IDEAS project for harmonisation of internal dosimetry.


Assuntos
Bioensaio/métodos , Guias de Prática Clínica como Assunto , Radiometria/métodos , Carga Corporal (Radioterapia) , Europa (Continente) , Fidelidade a Diretrizes , Doses de Radiação , Sensibilidade e Especificidade
10.
Radiat Prot Dosimetry ; 127(1-4): 339-42, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18045799

RESUMO

The IDEAS Guidelines for the assessment of internal doses from monitoring data suggest default measurement uncertainties (i.e. scattering factors, SFs) to be used for different types of monitoring data. However, these default values were mainly based upon expert judgement. In this paper, SF values have been calculated for different radionuclides and types of monitoring data using real data contained in the IDEAS Internal Contamination Database. Results are presented.


Assuntos
Bioensaio/estatística & dados numéricos , Bioensaio/normas , Fidelidade a Diretrizes/estatística & dados numéricos , Fidelidade a Diretrizes/normas , Guias de Prática Clínica como Assunto , Radiometria/estatística & dados numéricos , Radiometria/normas , Carga Corporal (Radioterapia) , União Europeia , Humanos , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
12.
Ann ICRP ; 46(3-4): 1-486, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29380630

RESUMO

Abstract ­: The 2007 Recommendations of the International Commission on Radiological Protection (ICRP, 2007) introduced changes that affect the calculation of effective dose, and implied a revision of the dose coefficients for internal exposure, published previously in the Publication 30 series (ICRP, 1979, 1980, 1981, 1988) and Publication 68 (ICRP, 1994). In addition, new data are now available that support an update of the radionuclide-specific information given in Publications 54 and 78 (ICRP, 1988a, 1997b) for the design of monitoring programmes and retrospective assessment of occupational internal doses. Provision of new biokinetic models, dose coefficients, monitoring methods, and bioassay data was performed by Committee 2, Task Group 21 on Internal Dosimetry, and Task Group 4 on Dose Calculations. A new series, the Occupational Intakes of Radionuclides (OIR) series, will replace the Publication 30 series and Publications 54, 68, and 78. OIR Part 1 has been issued (ICRP, 2015), and describes the assessment of internal occupational exposure to radionuclides, biokinetic and dosimetric models, methods of individual and workplace monitoring, and general aspects of retrospective dose assessment. OIR Part 2 (ICRP, 2016), this current publication and upcoming publications in the OIR series (Parts 4 and 5) provide data on individual elements and their radioisotopes, including information on chemical forms encountered in the workplace; a list of principal radioisotopes and their physical half-lives and decay modes; the parameter values of the reference biokinetic model; and data on monitoring techniques for the radioisotopes encountered most commonly in workplaces. Reviews of data on inhalation, ingestion, and systemic biokinetics are also provided for most of the elements. Dosimetric data provided in the printed publications of the OIR series include tables of committed effective dose per intake (Sv Bq−1 intake) for inhalation and ingestion, tables of committed effective dose per content (Sv Bq−1 measurement) for inhalation, and graphs of retention and excretion data per Bq intake for inhalation. These data are provided for all absorption types and for the most common isotope(s) of each element. The electronic annex that accompanies the OIR series of publications contains a comprehensive set of committed effective and equivalent dose coefficients, committed effective dose per content functions, and reference bioassay functions. Data are provided for inhalation, ingestion, and direct input to blood. This third publication in the series provides the above data for the following elements: ruthenium (Ru), antimony (Sb), tellurium (Te), iodine (I), caesium (Cs), barium (Ba), iridium (Ir), lead (Pb), bismuth (Bi), polonium (Po), radon (Rn), radium (Ra), thorium (Th), and uranium (U).


Assuntos
Exposição Ocupacional/prevenção & controle , Saúde Ocupacional/normas , Exposição à Radiação/prevenção & controle , Monitoramento de Radiação/normas , Proteção Radiológica/normas , Radioisótopos/efeitos adversos , Relação Dose-Resposta à Radiação , Humanos , Exposição à Radiação/normas , Radiação Ionizante , Medição de Risco
13.
Ann ICRP ; 45(3-4): 7-349, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28657340

RESUMO

Abstract ­: The 2007 Recommendations of the International Commission on Radiological Protection (ICRP, 2007) introduced changes that affect the calculation of effective dose, and implied a revision of the dose coefficients for internal exposure, published previously in the Publication 30 series (ICRP, 1979, 1980, 1981, 1988b) and Publication 68 (ICRP, 1994b). In addition, new data are available that support an update of the radionuclide-specific information given in Publications 54 and 78 (ICRP, 1988a, 1997b) for the design of monitoring programmes and retrospective assessment of occupational internal doses. Provision of new biokinetic models, dose coefficients, monitoring methods, and bioassay data was performed by Committee 2, Task Group 21 on Internal Dosimetry, and Task Group 4 on Dose Calculations. A new series, the Occupational Intakes of Radionuclides (OIR) series, will replace the Publication 30 series and Publications 54, 68, and 78. Part 1 of the OIR series has been issued (ICRP, 2015), and describes the assessment of internal occupational exposure to radionuclides, biokinetic and dosimetric models, methods of individual and workplace monitoring, and general aspects of retrospective dose assessment. The following publications in the OIR series (Parts 2­5) will provide data on individual elements and their radioisotopes, including information on chemical forms encountered in the workplace; a list of principal radioisotopes and their physical half-lives and decay modes; the parameter values of the reference biokinetic model; and data on monitoring techniques for the radioisotopes encountered most commonly in workplaces. Reviews of data on inhalation, ingestion, and systemic biokinetics are also provided for most of the elements. Dosimetric data provided in the printed publications of the OIR series include tables of committed effective dose per intake (Sv per Bq intake) for inhalation and ingestion, tables of committed effective dose per content (Sv per Bq measurement) for inhalation, and graphs of retention and excretion data per Bq intake for inhalation. These data are provided for all absorption types and for the most common isotope(s) of each element. The electronic annex that accompanies the OIR series of reports contains a comprehensive set of committed effective and equivalent dose coefficients, committed effective dose per content functions, and reference bioassay functions. Data are provided for inhalation, ingestion, and direct input to blood. The present publication provides the above data for the following elements: hydrogen (H), carbon (C), phosphorus (P), sulphur (S), calcium (Ca), iron (Fe), cobalt (Co), zinc (Zn), strontium (Sr), yttrium (Y), zirconium (Zr), niobium (Nb), molybdenum (Mo), and technetium (Tc).


Assuntos
Exposição Ocupacional/prevenção & controle , Exposição à Radiação/prevenção & controle , Monitoramento de Radiação/normas , Proteção Radiológica/normas , Radioisótopos , Relação Dose-Resposta à Radiação , Humanos , Saúde Ocupacional , Radiação Ionizante , Radiometria , Medição de Risco , Fatores de Risco
14.
Health Phys ; 71(1): 37-44, 1996 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-8655327

RESUMO

The dynamics of internal doses from 137CS and 90Sr as a consequence of the use of Dnieper River water were calculated. Local peculiarities of municipal tap, irrigation, and fish consumption in the Ukraine were considered. The dynamics of 90Sr accumulation in human bone as a result of the use of Dnieper water is simulated. The dose predictions are based on de facto data and the stochastic forecast of radionuclide concentrations in Dnieper reservoirs. A large array of statistical data on the age-structures of exposed populations, food consumption rate, agricultural production, fish contamination, and site-specific parameters were used. Exposures are estimated for 12 regions of the Dnieper basin and the Crimea Republic. The maximal individual annual committed effective doses are 1.7 X 10(-5) and 2.7 X 10(-5) Sv from 90Sr and 137Cs, respectively, due to the use of water in 1986 by members of the population in the Kievska region. Commercial fishermen on the Kievska reservoir, who consumed 360 kg y(-1) of fish in 1986, received 4.7 X 10(-4) and 5 X 10(-3) Sv from 90Sr and 137Cs, respectively. The contributions to the collective (over 70 y) effective dose of irrigation, municipal tap water, and fish consumption for members of the general public, respectively, are 18%, 43%, 39% in the Kievska region; 8%, 25%, 67% in the Poltavska region; 50% 50%, 0% (no Dnieper fish consumed) in the Crimea Republic. The predicted contribution of 90Sr to collective dose resulting from the use of water is 80%. The collective dose to the population of the Dnieper regions (32.5 million people) is 3,000 person-Sv, due to the use of water.


Assuntos
Reatores Nucleares , Doses de Radiação , Liberação Nociva de Radioativos , Poluentes Radioativos da Água/análise , Abastecimento de Água/análise , Radioisótopos de Césio/análise , Humanos , Radioisótopos de Estrôncio/análise , Ucrânia
15.
Health Phys ; 71(1): 19-28, 1996 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-8655324

RESUMO

The results of radiation monitoring data and migration pathway analysis of water bodies within areas affected by the 1986 Chernobyl accident provide a unique opportunity for decision-makers working in other extensively contaminated regions to optimize their approaches to surface and groundwater protection. Most engineering measures within the Chernobyl 30-km exclusion zone were focused on preventing secondary contamination of surface and groundwater from entering the Pripyat River and the Kiev Reservoir. However, implementation of these measures required huge financial and human resources. Therefore, lessons about post-accidental water protection activities can be learned from the Chernobyl example.


Assuntos
Centrais Elétricas , Liberação Nociva de Radioativos , Poluentes Radioativos da Água/toxicidade , Humanos , Reatores Nucleares , Risco , Ucrânia
16.
Radiat Prot Dosimetry ; 105(1-4): 399-402, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-14526996

RESUMO

The purposes of this study were to investigate the influence of the consequences of the lack of primary bioassay information and to elaborate approaches which could improve the reliability of dose assessments. The aggregated time-dependent functions 'dose per unit organ (excretion) content' z(t) have been proposed in this study as a convenient and reliable tool for bioassay. The analysis of the variation of z with changes of AMAD has demonstrated the existence of areas of the relative invariance of z, which permits the selection of one (reference) function z for the whole area of stability. Within the framework of such an approach an arbitrary set of bioassay data can be approximated by the linear combination F(t) = sum(i) E(i)/z(t - tau(i)), where F(t) = function of time t, which approximates the observed bioassay time trend; tau(i) = time shift of the acute intake i; E(i) = effective dose, associated with the acute intake i (the two last parameters are results of the approximation procedure).


Assuntos
Poluentes Radioativos do Ar/farmacocinética , Poluentes Radioativos do Ar/urina , Exposição por Inalação/análise , Pulmão/metabolismo , Modelos Biológicos , Modelos Estatísticos , Radiometria/métodos , Poluentes Radioativos do Ar/análise , Humanos , Taxa de Depuração Metabólica , Exposição Ocupacional/análise , Controle de Qualidade , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
17.
Radiat Prot Dosimetry ; 105(1-4): 265-8, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-14526968

RESUMO

This paper discusses the biokinetic and dosimetric models adopted in ICRP Publication 88 for the evaluation of fetal doses resulting from maternal intakes of radioiodine. The biokinetic model is used to simulate the behaviour of iodine in both the mother and the fetus. Such simulations provide the basis for the estimation of the dose to the embryo and determine the distribution of maternal iodine at the beginning of the fetal period. The model considers iodine to accumulate in the fetal thyroid from the 11th week. The dose to the fetus delivered following birth is evaluated with the biokinetic and dosimetric models described in ICRP Publication 67. Although a substantial fraction of the emitted energy of electrons and photons is less than 10 keV, conventionally assumed to be non-penetrating radiation, these emissions can escape the small fetal thyroid. Absorbed fractions for both self-dose and crossfire were evaluated for the requirements of radioiodine dosimetry in ICRP Publication 88.


Assuntos
Radioisótopos do Iodo/administração & dosagem , Radioisótopos do Iodo/farmacocinética , Troca Materno-Fetal/fisiologia , Modelos Biológicos , Radiometria/métodos , Glândula Tireoide/embriologia , Glândula Tireoide/metabolismo , Administração Oral , Simulação por Computador , Feminino , Idade Gestacional , Humanos , Exposição Materna , Gravidez , Doses de Radiação , Radiometria/normas , Medição de Risco/métodos , Distribuição Tecidual
18.
Radiat Prot Dosimetry ; 105(1-4): 341-6, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-14526983

RESUMO

Internal dose determination is an essential component of individual monitoring programmes for workers or members of the public exposed to radionuclides, and methods and computer programs are required for dose assessment. A recent international European Radiation Dosimetry Group (EURADOS) intercomparison has shown unacceptably large ranges in the results assessment. An ICRP working party has been initiated to consider what guidance ICRP can give on the use of models and interpret bioassay data in terms of intake/dose. In this field, six codes for bioassay data interpretation, which implement the current ICRP publication 78 biokinetic models, have been reviewed against several criteria with different levels of importance: minor criteria such as the practical use of the code and the graphical capabilities, and major criteria such as the choice of available parameters, peculiarities of data fitting and interpretation, the choice of biokinetic models and the use of uncertainties. All these criteria were assessed using one artificial set of data and two examples extracted from the previous international EURADOS intercomparison.


Assuntos
Radioisótopos de Césio/análise , Radioisótopos de Césio/farmacocinética , Modelos Biológicos , Plutônio/análise , Plutônio/farmacocinética , Radiometria/métodos , Software , Administração Oral , Contaminação Radioativa do Ar/análise , Radioisótopos de Césio/administração & dosagem , Radioisótopos de Césio/urina , Humanos , Exposição por Inalação/análise , Plutônio/urina , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Validação de Programas de Computador
19.
Radiat Prot Dosimetry ; 105(1-4): 427-32, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-14527002

RESUMO

When a set of bioassay data is given to two different dosimetrists, it is likely that these data will be interpreted differently, that different methods and dosimetric models will be applied and therefore different numerical values will be obtained. Thus, it is important for laboratories dealing with internal dosimetry to undergo performance testing procedures such as interlaboratory comparisons of bioassay data interpretation. Several intercomparison exercises have already been organised at national and international levels. The largest one so far was the 3rd European Intercomparison Exercise on Internal Dose Assessment, which has been organised in the framework of the EULEP/EURADOS Action Group, 'Derivation of parameter values for application to the new model of the human respiratory tract for occupational exposure'. The most important lesson learned from these intercomparison exercises was the need to develop agreed guidelines for internal dose evaluation procedures to promote harmonisation of assessments between organisations and countries.


Assuntos
Benchmarking/métodos , Modelos Biológicos , Proteção Radiológica/normas , Radioisótopos/análise , Radioisótopos/farmacocinética , Radiometria/métodos , Radiometria/estatística & dados numéricos , Simulação por Computador , Comportamento Cooperativo , Europa (Continente) , Humanos , Relações Interinstitucionais , Variações Dependentes do Observador , Exposição Ocupacional/análise , Doses de Radiação , Proteção Radiológica/métodos , Proteção Radiológica/estatística & dados numéricos , Poluentes Radioativos/análise , Radiometria/normas , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
20.
Radiat Prot Dosimetry ; 105(1-4): 645-7, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-14527042

RESUMO

Several international inter-comparison exercises on intake and internal dose assessments from monitoring data led to the conclusion that the results calculated by different participants varied significantly, mainly due to the broad variety of methods and assumptions applied in the assessment procedure. Based on these experiences, the need of harmonisation of the procedures has been formulated as an EU research project under the 5th Framework Programme, with the aim of developing general guidelines for standardising assessments of intakes and internal doses. In the IDEAS project, eight institutions from seven European countries are participating, also using inputs from internal dosimetry professionals from across Europe to ensure broad consensus in the outcome of the project. To ensure that the guidelines are applicable to a wide range of practical situations, the first step will be to compile a database on well documented cases of internal contamination. In parallel, an improved version of existing software will be developed and distributed to the partners for further use. Many cases from the database will be evaluated independently by more partners using the same software and the results will be discussed and the draft guidelines prepared. The guidelines will then be revised and refined on the basis of the experiences and discussions of two workshops, and an intercomparison exercise organised in the frame of the project which will be open to all internal dosimetry professionals.


Assuntos
Bases de Dados Factuais/normas , Guias como Assunto , Exposição Ocupacional/análise , Radiometria/métodos , Radiometria/normas , Projetos de Pesquisa , Sociedades Científicas/organização & administração , Carga Corporal (Radioterapia) , Monitoramento Ambiental/métodos , Monitoramento Ambiental/normas , União Europeia , Humanos , Cooperação Internacional , Organizações , Doses de Radiação
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