Detalhe da pesquisa
1.
Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart.
PLoS Biol
; 19(1): e3001062, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33395408
2.
MicroRNA Nanotherapeutics for Lung Targeting. Insights into Pulmonary Hypertension.
Int J Mol Sci
; 21(9)2020 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375361
3.
PHD3-SUMO conjugation represses HIF1 transcriptional activity independently of PHD3 catalytic activity.
J Cell Sci
; 128(1): 40-9, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25380826
4.
Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia.
J Biol Chem
; 287(12): 9651-8, 2012 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22308030
5.
Deciphering the emerging role of SUMO conjugation in the hypoxia-signaling cascade.
Biol Chem
; 394(4): 459-69, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23362194
6.
HIF-1α inhibitor PX-478 preserves pancreatic ß cell function in diabetes.
Sci Transl Med
; 14(638): eaba9112, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353540
7.
PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer.
Oncogenesis
; 11(1): 10, 2022 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197445
8.
Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites.
J Biol Chem
; 285(24): 18217-24, 2010 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20368331
9.
HIF-1alpha mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour.
Cell Microbiol
; 12(5): 640-53, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20039880
10.
PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.
Proc Natl Acad Sci U S A
; 105(12): 4745-50, 2008 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18347341
11.
The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase.
FEBS J
; 288(20): 5943-5963, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33844468
12.
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate.
Emerg Microbes Infect
; 10(1): 1065-1076, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34013835
13.
Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions.
Redox Biol
; 41: 101885, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33581682
14.
The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes.
Gut Microbes
; 13(1): 1939598, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34224309
15.
Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Nat Aging
; 1(4): 385-399, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37117599
16.
Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization.
Circulation
; 120(1): 50-9, 2009 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19546390
17.
Hypoxia-inducible factor 1{alpha} is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells.
J Cell Biol
; 170(1): 49-59, 2005 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15983061
18.
Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis.
Cancers (Basel)
; 12(9)2020 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32932846
19.
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer.
EBioMedicine
; 40: 406-421, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30594553
20.
Altered Stra13 and Dec2 circadian gene expression in hypoxic cells.
Biochem Biophys Res Commun
; 369(4): 1184-9, 2008 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18342625