Detalhe da pesquisa
1.
DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression.
EMBO Rep
; 24(8): e56233, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37382163
2.
Correction: Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity.
PLoS Pathog
; 16(12): e1009174, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33351850
3.
Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity.
PLoS Pathog
; 16(7): e1008654, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32673372
4.
Integrating large-scale neuroimaging research datasets: Harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets.
Neuroimage
; 237: 118189, 2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34022383
5.
C. elegans detects toxicity of traumatic brain injury generated tau.
Neurobiol Dis
; 153: 105330, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33711491
6.
Doxycycline rescues recognition memory and circadian motor rhythmicity but does not prevent terminal disease in fatal familial insomnia mice.
Neurobiol Dis
; 158: 105455, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358614
7.
Sleep inhibition induced by amyloid-ß oligomers is mediated by the cellular prion protein.
J Sleep Res
; 30(3): e13187, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32902030
8.
Cyclophillin A deficiency accelerates RML-induced prion disease.
Neurobiol Dis
; 130: 104498, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31181281
9.
Induction of a transmissible tau pathology by traumatic brain injury.
Brain
; 141(9): 2685-2699, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30084913
10.
Inhibition of IL-1ß Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease.
J Neurosci
; 37(43): 10278-10289, 2017 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28924012
11.
Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.
PLoS Pathog
; 11(4): e1004796, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25880443
12.
The c-jun N-terminal kinase plays a key role in ocular degenerative changes in a mouse model of Alzheimer disease suggesting a correlation between ocular and brain pathologies.
Oncotarget
; 8(47): 83038-83051, 2017 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29137322
13.
Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms.
Neurobiol Aging
; 23(5): 957-76, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12392798
14.
Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 Subunit.
Neuron
; 74(2): 300-13, 2012 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22542184
15.
CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail.
J Biol Chem
; 283(44): 30101-11, 2008 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-18701457
16.
Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation.
J Biol Chem
; 281(42): 32048-56, 2006 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16935860
17.
CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome.
Hum Mol Genet
; 14(14): 1935-46, 2005 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15917271
18.
Tetracyclines affect prion infectivity.
Proc Natl Acad Sci U S A
; 99(16): 10849-54, 2002 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-12149459