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1.
Proc Natl Acad Sci U S A ; 118(40)2021 10 05.
Artigo em Inglês | MEDLINE | ID: mdl-34593630

RESUMO

Magnetic resonance fingerprinting (MRF) is a method to extract quantitative tissue properties such as [Formula: see text] and [Formula: see text] relaxation rates from arbitrary pulse sequences using conventional MRI hardware. MRF pulse sequences have thousands of tunable parameters, which can be chosen to maximize precision and minimize scan time. Here, we perform de novo automated design of MRF pulse sequences by applying physics-inspired optimization heuristics. Our experimental data suggest that systematic errors dominate over random errors in MRF scans under clinically relevant conditions of high undersampling. Thus, in contrast to prior optimization efforts, which focused on statistical error models, we use a cost function based on explicit first-principles simulation of systematic errors arising from Fourier undersampling and phase variation. The resulting pulse sequences display features qualitatively different from previously used MRF pulse sequences and achieve fourfold shorter scan time than prior human-designed sequences of equivalent precision in [Formula: see text] and [Formula: see text] Furthermore, the optimization algorithm has discovered the existence of MRF pulse sequences with intrinsic robustness against shading artifacts due to phase variation.


Assuntos
Imageamento por Ressonância Magnética/métodos , Algoritmos , Automação , Encéfalo/diagnóstico por imagem , Simulação por Computador , Epilepsia/diagnóstico por imagem , Humanos , Processamento de Imagem Assistida por Computador/métodos , Neoplasias/diagnóstico por imagem , Imagens de Fantasmas
2.
Phys Rev Lett ; 129(5): 050504, 2022 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-35960553

RESUMO

Quantum low density parity check (LDPC) codes may provide a path to build low-overhead fault-tolerant quantum computers. However, as general LDPC codes lack geometric constraints, naïve layouts couple many distant qubits with crossing connections which could be hard to build in hardware and could result in performance-degrading crosstalk. We propose a 2D layout for quantum LDPC codes by decomposing their Tanner graphs into a small number of planar layers. Each layer contains long-range connections which do not cross. For any Calderbank-Shor-Steane code with a degree-δ Tanner graph, we design stabilizer measurement circuits with depth at most (2δ+2) using at most ⌈δ/2⌉ layers. We observe a circuit-noise threshold of 0.28% for a positive-rate code family using 49 physical qubits per logical qubit. For a physical error rate of 10^{-4}, this family reaches a logical error rate of 10^{-15} using fourteen times fewer physical qubits than the surface code.

3.
Phys Rev Lett ; 120(18): 180501, 2018 May 04.
Artigo em Inglês | MEDLINE | ID: mdl-29775352

RESUMO

Three-dimensional (3D) color codes have advantages for fault-tolerant quantum computing, such as protected quantum gates with relatively low overhead and robustness against imperfect measurement of error syndromes. Here we investigate the storage threshold error rates for bit-flip and phase-flip noise in the 3D color code (3DCC) on the body-centered cubic lattice, assuming perfect syndrome measurements. In particular, by exploiting a connection between error correction and statistical mechanics, we estimate the threshold for 1D stringlike and 2D sheetlike logical operators to be p_{3DCC}^{(1)}≃1.9% and p_{3DCC}^{(2)}≃27.6%. We obtain these results by using parallel tempering Monte Carlo simulations to study the disorder-temperature phase diagrams of two new 3D statistical-mechanical models: the four- and six-body random coupling Ising models.

4.
Phys Rev Lett ; 120(2): 025301, 2018 Jan 12.
Artigo em Inglês | MEDLINE | ID: mdl-29376692

RESUMO

We show that Ramsey spectroscopy of fermionic alkaline-earth atoms in a square-well trap provides an efficient and accurate estimate for the eigenspectrum of a density matrix whose n copies are stored in the nuclear spins of n such atoms. This spectrum estimation is enabled by the high symmetry of the interaction Hamiltonian, dictated, in turn, by the decoupling of the nuclear spin from the electrons and by the shape of the square-well trap. Practical performance of this procedure and its potential applications to quantum computing and time keeping with alkaline-earth atoms are discussed.

5.
Phys Rev E ; 101(4-1): 042117, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32422760

RESUMO

In statistical mechanics, a small system exchanges conserved quantities-heat, particles, electric charge, etc.-with a bath. The small system thermalizes to the canonical ensemble or the grand canonical ensemble, etc., depending on the quantities. The conserved quantities are represented by operators usually assumed to commute with each other. This assumption was removed within quantum-information-theoretic (QI-theoretic) thermodynamics recently. The small system's long-time state was dubbed "the non-Abelian thermal state (NATS)." We propose an experimental protocol for observing a system thermalize to the NATS. We illustrate with a chain of spins, a subset of which forms the system of interest. The conserved quantities manifest as spin components. Heisenberg interactions push the conserved quantities between the system and the effective bath, the rest of the chain. We predict long-time expectation values, extending the NATS theory from abstract idealization to finite systems that thermalize with finite couplings for finite times. Numerical simulations support the analytics: The system thermalizes to near the NATS, rather than to the canonical prediction. Our proposal can be implemented with ultracold atoms, nitrogen-vacancy centers, trapped ions, quantum dots, and perhaps nuclear magnetic resonance. This work introduces noncommuting conserved quantities from QI-theoretic thermodynamics into quantum many-body physics: atomic, molecular, and optical physics and condensed matter.

6.
Artigo em Inglês | MEDLINE | ID: mdl-31276073

RESUMO

We show that n thermal fermionic alkaline-earth-metal atoms in a flat-bottom trap allow one to robustly implement a spin model displaying two symmetries: the S n symmetry that permutes atoms occupying different vibrational levels of the trap and the SU(N) symmetry associated with N nuclear spin states. The symmetries make the model exactly solvable, which, in turn, enables the analytic study of dynamical processes such as spin diffusion in this SU(N) system. We also show how to use this system to generate entangled states that allow for Heisenberg-limited metrology. This highly symmetric spin model should be experimentally realizable even when the vibrational levels are occupied according to a high-temperature thermal or an arbitrary nonthermal distribution.

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