Detalhe da pesquisa
1.
High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers.
Bioconjug Chem
; 29(2): 473-485, 2018 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29425028
2.
Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates.
Pharm Res
; 32(6): 1884-93, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25446772
3.
Exploration of the antibody-drug conjugate clinical landscape.
MAbs
; 15(1): 2229101, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37639687
4.
Development of T-cell engagers selective for cells co-expressing two antigens.
MAbs
; 14(1): 2115213, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36206404
5.
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties.
J Med Chem
; 64(5): 2534-2575, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596065
6.
Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs.
J Immunol Methods
; 332(1-2): 41-52, 2008 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18230399
7.
An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.
Mol Cancer Ther
; 17(3): 638-649, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29282299
8.
bisFabs: Tools for rapidly screening hybridoma IgGs for their activities as bispecific antibodies.
MAbs
; 9(3): 430-437, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28125314
9.
Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates.
Chem Sci
; 8(1): 366-370, 2017 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28451181
10.
Site-specific antibody drug conjugates for cancer therapy.
MAbs
; 6(1): 34-45, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24423619
11.
Development of a semi-automated high throughput transient transfection system.
J Biotechnol
; 180: 10-6, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24704608
12.
An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins.
MAbs
; 6(1): 95-107, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121517
13.
Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.
Mol Cancer Ther
; 18(11): 2182, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31676543
14.
Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering.
J Med Chem
; 57(19): 7890-9, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25191794
15.
Engineering THIOMABs for site-specific conjugation of thiol-reactive linkers.
Methods Mol Biol
; 1045: 189-203, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23913148
16.
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.
Nat Biotechnol
; 30(2): 184-9, 2012 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22267010
17.
Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer.
Clin Cancer Res
; 16(19): 4769-78, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805300
18.
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.
Nat Biotechnol
; 26(8): 925-32, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18641636