RESUMO
A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with severe acute respiratory syndrome coronavirus 2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high-dose intravenous methylprednisolone, tocilizumab, and intravenous immunoglobulin with significant short-term clinical improvement but long-term sequelae.
Assuntos
Encefalopatias , COVID-19 , Encefalopatias/diagnóstico , Encefalopatias/etiologia , COVID-19/complicações , Progressão da Doença , Humanos , Lactente , Metilprednisolona/uso terapêutico , NeuroimagemRESUMO
E-cigarette-and vaping-associated lung injury (EVALI) is a new diagnosis with at least 2,807 hospitalizations and 68 deaths since 2019. This clinical observation describes one of the first cases of EVALI in a teenager who presented with nic-sick symptoms and developed acute respiratory distress syndrome and pneumomediastinum. The manuscript also reviews the presentation, work-up, recommended management, and proposed etiology of the condition and summarizes recent national vaping regulations enacted to address the EVALI epidemic.
Assuntos
Sistemas Eletrônicos de Liberação de Nicotina , Lesão Pulmonar , Síndrome do Desconforto Respiratório , Insuficiência Respiratória , Vaping , Adolescente , Humanos , Síndrome do Desconforto Respiratório/etiologia , Insuficiência Respiratória/etiologia , Vaping/efeitos adversosRESUMO
We report a case of a 12-day-old term neonate with extended-spectrum beta-lactamase (ESBL) producing Escherichia coli (E. coli) meningitis and cerebral abscess. The patient received a 7-day course of antibiotics just few days prior to the infection. The incidence of infections from ESBL-producing E. coli is increasingly emerging. Antimicrobial agents must be vigilantly utilized to prevent the new highly resistant bacteria.