Detalhe da pesquisa
1.
Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study.
Lancet Oncol
; 18(1): 42-51, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27932068
2.
Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models.
Cancer Res
; 67(10): 4924-32, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17510422
3.
Prevalence of Delta-like protein 3 expression in patients with small cell lung cancer.
Lung Cancer
; 115: 116-120, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29290251
4.
Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies.
Oncotarget
; 8(43): 73419-73432, 2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29088717
5.
Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer.
Cancer Res
; 77(14): 3931-3941, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28487384
6.
EphB2 is a prognostic factor in colorectal cancer.
Clin Cancer Res
; 11(14): 5181-7, 2005 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16033834
7.
COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas.
Cancer Res
; 64(20): 7226-30, 2004 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15492238
8.
Initiation and characterization of small cell lung cancer patient-derived xenografts from ultrasound-guided transbronchial needle aspirates.
PLoS One
; 10(5): e0125255, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25955027
9.
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.
Sci Transl Med
; 7(302): 302ra136, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26311731
10.
Phosphorous dysregulation induced by MEK small molecule inhibitors in the rat involves blockade of FGF-23 signaling in the kidney.
Toxicol Sci
; 125(1): 187-95, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21976371
11.
Effects of anti-VEGF on pharmacokinetics, biodistribution, and tumor penetration of trastuzumab in a preclinical breast cancer model.
Mol Cancer Ther
; 11(3): 752-62, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22222630
12.
Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.
PLoS One
; 6(7): e22595, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21799911