Detalhe da pesquisa
1.
Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both chromosomes 1q32 and 10q26.
Proc Natl Acad Sci U S A
; 119(20): e2118510119, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35561216
2.
Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.
Am J Hum Genet
; 108(8): 1385-1400, 2021 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260948
3.
Spatial distribution of metabolites in the retina and its relevance to studies of metabolic retinal disorders.
Metabolomics
; 19(2): 10, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36745234
4.
Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization.
Exp Eye Res
; 215: 108908, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34954204
5.
Prevalence and phenotype associations of complement factor I mutations in geographic atrophy.
Hum Mutat
; 42(9): 1139-1152, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34153144
6.
Viral Transduction of Human Rod Opsin or Channelrhodopsin Variants to Mouse ON Bipolar Cells Does Not Impact Retinal Anatomy or Cause Measurable Death in the Targeted Cells.
Int J Mol Sci
; 22(23)2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884916
7.
Association of plasma trace element levels with neovascular age-related macular degeneration.
Exp Eye Res
; 201: 108324, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33098886
8.
Intravitreal Pharmacokinetic Study of the Antiangiogenic Glycoprotein Opticin.
Mol Pharm
; 17(7): 2390-2397, 2020 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32437164
9.
Loss-of-Function Mutations in the CFH Gene Affecting Alternatively Encoded Factor H-like 1 Protein Cause Dominant Early-Onset Macular Drusen.
Ophthalmology
; 126(10): 1410-1421, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905644
10.
Molecular findings from 537 individuals with inherited retinal disease.
J Med Genet
; 53(11): 761-767, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27208204
11.
Whole Genome Sequencing Increases Molecular Diagnostic Yield Compared with Current Diagnostic Testing for Inherited Retinal Disease.
Ophthalmology
; 123(5): 1143-50, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26872967
12.
Characterisation of the metabolome of ocular tissues and post-mortem changes in the rat retina.
Exp Eye Res
; 149: 8-15, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233448
13.
Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.
J Immunol
; 193(10): 4962-70, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25305316
14.
Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.
Hum Mol Genet
; 22(23): 4857-69, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873044
15.
Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease.
Biochem Biophys Res Commun
; 460(3): 549-54, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25797622
16.
Routine versus As-Needed Bevacizumab with 12-Weekly Assessment Intervals for Neovascular Age-Related Macular Degeneration: 92-Week Results of the GMAN Trial.
Ophthalmology
; 122(7): 1348-55, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25892016
17.
The role of extracellular matrix in retinal vascular development and preretinal neovascularization.
Exp Eye Res
; 133: 30-6, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25819452
18.
Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions.
J Immunol
; 190(5): 2049-57, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23365078
19.
Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.
Hum Mol Genet
; 21(18): 4138-50, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22694956
20.
Repeatability of visual function measures in age-related macular degeneration.
Graefes Arch Clin Exp Ophthalmol
; 252(2): 201-6, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23884391