Detalhe da pesquisa
1.
Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells.
Cell
; 175(6): 1546-1560.e17, 2018 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30500537
2.
TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease.
Cell
; 171(1): 10-13, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888322
3.
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.
Cell
; 171(7): 1545-1558.e18, 2017 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29153836
4.
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.
Cell
; 184(8): 2255, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861965
5.
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Cell
; 184(8): 2256, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861966
6.
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1.
Mol Cell
; 83(16): 3010-3026.e8, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595559
7.
Raymond L. Erikson (1936-2020).
Cell
; 181(5): 961-963, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074798
8.
The intrinsic substrate specificity of the human tyrosine kinome.
Nature
; 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720073
9.
An atlas of substrate specificities for the human serine/threonine kinome.
Nature
; 613(7945): 759-766, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36631611
10.
mTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Mol Cell
; 81(10): 2064-2075.e8, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33756105
11.
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Cell
; 153(4): 840-54, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23663782
12.
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
Proc Natl Acad Sci U S A
; 121(21): e2403685121, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38743625
13.
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Nature
; 585(7824): 283-287, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814897
14.
Ran-Binding Protein 3 Phosphorylation Links the Ras and PI3-Kinase Pathways to Nucleocytoplasmic Transport.
Mol Cell
; 83(22): 4190, 2023 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37980093
15.
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation.
Mol Cell
; 70(5): 949-960.e4, 2018 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29861159
16.
Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.
Mol Cell
; 67(3): 512-527.e4, 2017 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757207
17.
Structural Insights into the Activation of mTORC1 on the Lysosomal Surface.
Trends Biochem Sci
; 45(5): 367-369, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32311329
18.
Editorial Note to: Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply.
Mol Cell
; 81(14): 3031, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270944
19.
mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33649236
20.
The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Genes Dev
; 30(22): 2551-2564, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913603