Detalhe da pesquisa
1.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
N Engl J Med
; 387(21): 1923-1934, 2022 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36342113
2.
Long-term efficacy and safety of lerodalcibep in heterozygous familial hypercholesterolaemia: the LIBerate-HeFH trial.
Eur Heart J
; 44(40): 4272-4280, 2023 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37639462
3.
Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study.
Lancet
; 399(10326): 719-728, 2022 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35101175
4.
Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.
N Engl J Med
; 381(6): 531-542, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31390500
5.
Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms.
Curr Atheroscler Rep
; 24(6): 399-405, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355214
6.
Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town.
Arterioscler Thromb Vasc Biol
; 41(2): 934-943, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147992
7.
RNA-based therapy in the management of lipid disorders: a review.
Lipids Health Dis
; 21(1): 41, 2022 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35459248
8.
Lipoprotein metabolism in familial hypercholesterolemia.
J Lipid Res
; 62: 100062, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675717
9.
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.
N Engl J Med
; 376(17): 1647-1658, 2017 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28402248
10.
Lomitapide and Mipomersen-Inhibiting Microsomal Triglyceride Transfer Protein (MTP) and apoB100 Synthesis.
Curr Atheroscler Rep
; 21(12): 48, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31741187
11.
Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab.
Arterioscler Thromb Vasc Biol
; 38(3): 592-598, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284604
12.
Survival in homozygous familial hypercholesterolaemia is determined by the on-treatment level of serum cholesterol.
Eur Heart J
; 39(14): 1162-1168, 2018 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29106543
13.
Efficacy and safety of evolocumab in reducing lipids and cardiovascular events.
N Engl J Med
; 372(16): 1500-9, 2015 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25773607
14.
A 52-week placebo-controlled trial of evolocumab in hyperlipidemia.
N Engl J Med
; 370(19): 1809-19, 2014 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24678979
15.
Effects of Evolocumab on Vitamin E and Steroid Hormone Levels: Results From the 52-Week, Phase 3, Double-Blind, Randomized, Placebo-Controlled DESCARTES Study.
Circ Res
; 117(8): 731-41, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26228031
16.
Evaluation of the efficacy, safety and glycaemic effects of evolocumab (AMG 145) in hypercholesterolaemic patients stratified by glycaemic status and metabolic syndrome.
Diabetes Obes Metab
; 19(1): 98-107, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27619750
17.
Proprotein Convertase Subtilisin Kexin Type 9 Inhibition for Autosomal Recessive Hypercholesterolemia-Brief Report.
Arterioscler Thromb Vasc Biol
; 36(8): 1647-50, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27079874
18.
PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role.
J Lipid Res
; 57(6): 1086-96, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102113
19.
Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial.
Lancet
; 385(9965): 341-50, 2015 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25282520
20.
Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated doses of statins: the ODYSSEY COMBO II randomized controlled trial.
Eur Heart J
; 36(19): 1186-94, 2015 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25687353