Detalhe da pesquisa
1.
Selective activation of PFKL suppresses the phagocytic oxidative burst.
Cell
; 184(17): 4480-4494.e15, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320407
2.
Activity-based profiling of proteases.
Annu Rev Biochem
; 83: 249-73, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24905783
3.
PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells.
Immunity
; 49(2): 247-263.e7, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054205
4.
Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron.
Nat Chem Biol
; 19(12): 1469-1479, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37349583
5.
Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.
J Am Chem Soc
; 146(10): 6880-6892, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38411555
6.
A protease-activated, near-infrared fluorescent probe for early endoscopic detection of premalignant gastrointestinal lesions.
Proc Natl Acad Sci U S A
; 118(1)2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33443161
7.
The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis.
PLoS Pathog
; 16(9): e1008852, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32960931
8.
Structure- and function-based design of Plasmodium-selective proteasome inhibitors.
Nature
; 530(7589): 233-6, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26863983
9.
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents.
PLoS Pathog
; 15(6): e1007722, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31170268
10.
The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy.
Int J Mol Sci
; 22(1)2021 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33466458
11.
Uncovering an overlooked consequence of phosphorylation: change in cysteine reactivity.
Nat Methods
; 19(3): 281-283, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228728
12.
Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP).
Nat Chem Biol
; 14(6): 609-617, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29769740
13.
Pre-Trained Deep Convolutional Neural Network for Clostridioides Difficile Bacteria Cytotoxicity Classification Based on Fluorescence Images.
Sensors (Basel)
; 20(23)2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33255305
14.
Procathepsin V Is Secreted in a TSH Regulated Manner from Human Thyroid Epithelial Cells and Is Accessible to an Activity-Based Probe.
Int J Mol Sci
; 21(23)2020 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33266306
15.
Design of Optical-Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease-Tissue Extracts.
Angew Chem Int Ed Engl
; 59(43): 19143-19152, 2020 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589815
16.
Catalytic linkage between caspase activity and proteostasis in Archaea.
Environ Microbiol
; 21(1): 286-298, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30370585
17.
Synthetic and biological approaches to map substrate specificities of proteases.
Biol Chem
; 401(1): 165-182, 2019 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31639098
18.
An in vivo multiplexed small-molecule screening platform.
Nat Methods
; 13(10): 883-889, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27617390
19.
Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites.
PLoS Pathog
; 13(9): e1006586, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28922424
20.
Chemical Strategies To Target Bacterial Virulence.
Chem Rev
; 117(5): 4422-4461, 2017 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28234447