Detalhe da pesquisa
1.
SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.
Diabetologia
; 66(11): 2042-2061, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37537395
2.
A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.
J Biol Chem
; 298(1): 101431, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801552
3.
Nmp4, a Regulator of Induced Osteoanabolism, Also Influences Insulin Secretion and Sensitivity.
Calcif Tissue Int
; 110(2): 244-259, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417862
4.
Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic ß cell.
J Biol Chem
; 294(1): 168-181, 2019 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420428
5.
Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2ß (Group VIA Phospholipase A2).
J Biol Chem
; 291(44): 23268-23281, 2016 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27650501
6.
Combination Immunotherapy for Type 1 Diabetes.
Curr Diab Rep
; 17(7): 50, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28534310
7.
Calcium-independent phospholipases A2 and their roles in biological processes and diseases.
J Lipid Res
; 56(9): 1643-68, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26023050
8.
A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of ß cell stress in type 1 diabetes.
EBioMedicine
; 87: 104379, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36463755
9.
The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for ß-Cell Function In Vivo.
Diabetes
; 72(6): 746-757, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36913741
10.
Offspring of Obese Dams Exhibit Sex-Differences in Pancreatic Heparan Sulfate Glycosaminoglycans and Islet Insulin Secretion.
Front Endocrinol (Lausanne)
; 12: 658439, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34108935
11.
A Computational Approach for Defining a Signature of ß-Cell Golgi Stress in Diabetes.
Diabetes
; 69(11): 2364-2376, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820009
12.
Cigarette smoke exposure impairs ß-cell function through activation of oxidative stress and ceramide accumulation.
Mol Metab
; 37: 100975, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283079
13.
Lipid mediators and biomarkers associated with type 1 diabetes development.
JCI Insight
; 5(16)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814707
14.
Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic ß-Cell.
Diabetes
; 67(11): 2293-2304, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131394
15.
Inhibition of Ca2+-independent phospholipase A2ß (iPLA2ß) ameliorates islet infiltration and incidence of diabetes in NOD mice.
Diabetes
; 64(2): 541-54, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25213337
16.
Evidence of contribution of iPLA2ß-mediated events during islet ß-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2ß in T1D development.
Endocrinology
; 155(9): 3352-64, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25004092
17.
Genetic modulation of islet ß-cell iPLA2ß expression provides evidence for its impact on ß-cell apoptosis and autophagy.
Islets
; 5(1): 29-44, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23411472
18.
Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2ß): candidate drug for preventing beta-cell apoptosis and diabetes.
PLoS One
; 8(8): e71748, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977134
19.
Regeneration of pancreatic non-ß endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin.
PLoS One
; 7(5): e36675, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22586489
20.
Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts ß-cell survival and proliferation differentially in vitro and in vivo.
Islets
; 4(6): 366-78, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23183538