Detalhe da pesquisa
1.
TAPPing into the potential of inducible tau/APP transgenic mice.
Neuropathol Appl Neurobiol
; 48(3): e12791, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35067965
2.
Reactive astrocytes as treatment targets in Alzheimer's disease-Systematic review of studies using the APPswePS1dE9 mouse model.
Glia
; 69(8): 1852-1881, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33634529
3.
Phenotypic diversity in ALS and the role of poly-conformational protein misfolding.
Acta Neuropathol
; 142(1): 41-55, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32930869
4.
Supercharging Prions via Amyloid-Selective Lysine Acetylation.
Angew Chem Int Ed Engl
; 60(27): 15069-15079, 2021 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876528
5.
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
J Neurosci
; 39(27): 5404-5418, 2019 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31061090
6.
N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements.
Lab Invest
; 99(7): 1030-1040, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31019288
7.
Vulnerability of newly synthesized proteins to proteostasis stress.
J Cell Sci
; 129(9): 1892-901, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27026526
8.
Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease.
Acta Neuropathol
; 136(6): 919-938, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30140941
9.
Relationship between mutant Cu/Zn superoxide dismutase 1 maturation and inclusion formation in cell models.
J Neurochem
; 140(1): 140-150, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27727458
10.
Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice.
Hum Mol Genet
; 24(4): 1019-35, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25305079
11.
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Proc Natl Acad Sci U S A
; 111(29): 10732-7, 2014 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25002524
12.
Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer's disease.
Neurobiol Dis
; 96: 171-185, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27569580
13.
Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways.
Acta Neuropathol
; 131(1): 103-14, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26650262
14.
Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.
Acta Neuropathol
; 132(6): 827-840, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27704280
15.
Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.
Mol Ther
; 23(1): 53-62, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25228069
16.
Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy.
Proc Natl Acad Sci U S A
; 110(27): 10934-9, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23781106
17.
Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation.
J Neurochem
; 133(3): 452-64, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25557022
18.
Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis.
Hum Mol Genet
; 22(14): 2765-74, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23512986
19.
Characterization of Protein Structural Changes in Living Cells Using Time-Lapsed FTIR Imaging.
Anal Chem
; 87(12): 6025-31, 2015 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25965274
20.
Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.
J Neurosci
; 33(9): 3765-79, 2013 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23447589