Uvular Necrosis: Day-to-Day Progression of a Rare Postoperative Complication.

Uvular necrosis is a rare post-procedural complication thought to be caused by mechanical compression of the uvula during endotracheal intubation. We described the day-to-day progression of uvular necrosis after right shoulder acromioclavicular (AC) joint reconstruction. We present a case of a 22-year-old male who visited the emergency department after sustaining a right shoulder trauma. Diagnosis of a type V AC dislocation with total coracoclavicular ligament tear was established. On day one, after endotracheal intubation for the right shoulder AC joint reconstruction, the patient complained of severe throat pain that progressed to odynophagia, dysphagia, and choking. Examination revealed an erythematous uvula with well-demarcated necrotic tissue. He was managed conservatively with acetaminophen and ice chips. Day-to-day symptom progression description may guide physicians in managing postoperative uvular necrosis.

Hospitalization requiring intensive care unit due to SARS-CoV-2 infection correlated with IgM depression and IgG elevation.

AIM: This study investigated the humoral response against SARS-CoV-2 in patients needing intensive care unit (ICU) care compared with those on general medicine wards. MATERIALS & METHODS: The authors retrospectively reviewed 113 hospitalized patients with COVID-19. They assessed antibody response against five SARS-CoV-2 epitopes at 6-14 days post symptom onset in these patients. RESULTS: Patients with ICU admissions had decreased anti-nucleocapsid immunoglobulin (Ig)M and increased anti-spike IgG compared with patients not requiring the ICU. IgG levels were positively correlated with length of stay. CONCLUSION: Higher levels of IgG against the spike protein correlate with COVID-19 disease severity and length of stay in hospitalized patients. This adds to the knowledge of biochemical response to clinical disease and may help predict ICU needs.