Detalhe da pesquisa
1.
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Br J Clin Pharmacol
; 87(4): 2078-2088, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085781
2.
The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.
J Biol Chem
; 286(52): 44659-68, 2011 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21998306
3.
An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparum.
J Biol Chem
; 285(24): 18615-26, 2010 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20332090
4.
Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum.
Malar J
; 10: 42, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21320353
5.
Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes.
J Antimicrob Chemother
; 65(5): 906-16, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20237075
6.
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
medRxiv
; 2020 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511548
7.
Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.
Clin Pharmacol Ther
; 108(4): 775-790, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32438446
8.
Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.
Malar J
; 8: 38, 2009 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19267910
9.
Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates.
Bioorg Med Chem Lett
; 19(7): 2038-43, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19251414
10.
Antitumour and antimalarial activity of artemisinin-acridine hybrids.
Bioorg Med Chem Lett
; 19(7): 2033-7, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19249201
11.
A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites.
Biochem J
; 411(2): 287-95, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18215139
12.
Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex.
Mol Pharmacol
; 73(5): 1347-55, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18319379
13.
Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure.
Antimicrob Agents Chemother
; 52(11): 3883-8, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18725445
14.
The malaria parasite type II NADH:quinone oxidoreductase: an alternative enzyme for an alternative lifestyle.
Trends Parasitol
; 23(7): 305-10, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17499024
15.
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
Curr Top Med Chem
; 6(5): 479-507, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16719804
16.
Current drug development portfolio for antimalarial therapies.
Curr Opin Pharmacol
; 5(5): 473-8, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16084770
17.
Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.
AIDS
; 19(18): 2097-102, 2005 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16284458
18.
Malaria parasite transporters as a drug-delivery strategy.
Trends Parasitol
; 21(7): 299-301, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15923144
19.
Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum.
Biochem Pharmacol
; 70(8): 1158-66, 2005 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16139253
20.
Altered binding of chloroquine to ferriprotoporphyrin IX is the basis for chloroquine resistance.
Drug Resist Updat
; 2(2): 97-103, 1999 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11504477