Detalhe da pesquisa
1.
Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit.
Mol Psychiatry
; 27(3): 1805-1815, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165396
2.
Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.
EMBO J
; 34(17): 2255-71, 2015 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26165689
3.
GM130 gain-of-function induces cell pathology in a model of lysosomal storage disease.
Hum Mol Genet
; 21(7): 1481-95, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22156940
4.
Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning.
Elife
; 122023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37431882
5.
Storage vesicles in neurons are related to Golgi complex alterations in mucopolysaccharidosis IIIB.
Am J Pathol
; 177(6): 2984-99, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21037080
6.
GAP43 overexpression and enhanced neurite outgrowth in mucopolysaccharidosis type IIIB cortical neuron cultures.
J Neurosci Res
; 88(1): 202-13, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19658197
7.
Storage problems in lysosomal diseases.
Biochem Soc Trans
; 38(6): 1442-7, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21118104
8.
Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin.
Elife
; 92020 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32452382
9.
Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice.
EMBO Mol Med
; 12(2): e10889, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31913581
10.
Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington's Disease.
Cell Rep
; 22(1): 110-122, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29298414
11.
Heparan sulfate saccharides modify focal adhesions: implication in mucopolysaccharidosis neuropathophysiology.
J Mol Biol
; 427(4): 775-791, 2015 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25268803