Detalhe da pesquisa
1.
Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
Mol Cell
; 83(20): 3679-3691.e8, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797621
2.
Structural insights into BCDX2 complex function in homologous recombination.
Nature
; 619(7970): 640-649, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37344589
3.
Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
PLoS Genet
; 16(11): e1009117, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33201894
4.
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.
Proc Natl Acad Sci U S A
; 116(35): 17438-17443, 2019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395736
5.
DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.
J Biol Chem
; 292(26): 10779-10790, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28515316
6.
Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.
J Biol Chem
; 292(7): 2795-2804, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049724
7.
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.
Nature
; 489(7417): 581-4, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22960744
8.
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
PLoS Genet
; 11(12): e1005675, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684013
9.
EEPD1 promotes repair of oxidatively-stressed replication forks.
NAR Cancer
; 5(1): zcac044, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36683914
10.
DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation.
Nat Commun
; 14(1): 432, 2023 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36702902
11.
An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence.
NPJ Precis Oncol
; 7(1): 126, 2023 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38030881
12.
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.
Nucleic Acids Res
; 38(6): 1821-31, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20019063
13.
Bloom helicase mediates formation of large single-stranded DNA loops during DNA end processing.
Nat Commun
; 13(1): 2248, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35473934
14.
Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models.
Clin Cancer Res
; 28(17): 3836-3849, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35797217
15.
Targeting radioresistance and replication fork stability in prostate cancer.
JCI Insight
; 7(9)2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35349486
16.
Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition.
Mol Cancer Res
; 20(6): 938-948, 2022 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35191501
17.
EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation.
Nat Cell Biol
; 24(8): 1291-1305, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35915159
18.
Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.
EMBO Rep
; 10(6): 629-35, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19444312
19.
Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.
Nat Commun
; 12(1): 7014, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853306
20.
Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence.
Cancer Res
; 81(23): 5935-5947, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34580063