Detalhe da pesquisa
1.
Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
PLoS Genet
; 15(8): e1008295, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31398187
2.
Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport.
Hum Mol Genet
; 28(9): 1498-1514, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30590647
3.
Multi-Granulin Domain Peptides Bind to Pro-Cathepsin D and Stimulate Its Enzymatic Activity More Effectively Than Progranulin in Vitro.
Biochemistry
; 58(23): 2670-2674, 2019 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31099551
4.
The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.
J Neurosci
; 35(25): 9315-28, 2015 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26109656
5.
Selective chemical intervention in the proteome of Caenorhabditis elegans.
J Proteome Res
; 9(11): 6060-70, 2010 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20804218
6.
D-cycloserine potentiates the reconsolidation of cocaine-associated memories.
Learn Mem
; 16(1): 82-5, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19144966
7.
Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors.
J Neurosci
; 28(33): 8230-7, 2008 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18701685
8.
Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy.
NPJ Aging Mech Dis
; 5: 7, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31602311
9.
Progranulin Stimulates the In Vitro Maturation of Pro-Cathepsin D at Acidic pH.
J Mol Biol
; 431(5): 1038-1047, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30690031
10.
The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response.
Methods Mol Biol
; 1806: 193-206, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29956278
11.
A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans.
J R Soc Interface
; 12(102): 20140963, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25551155