Detalhe da pesquisa
1.
Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.
Bioorg Med Chem Lett
; 95: 129487, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734423
2.
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.
Alzheimers Dement
; 12(6): 645-53, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27079753
3.
Protein Networks Associated with Native Metabotropic Glutamate 1 Receptors (mGlu1) in the Mouse Cerebellum.
Cells
; 12(9)2023 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37174725
4.
Degree Adjusted Large-Scale Network Analysis Reveals Novel Putative Metabolic Disease Genes.
Biology (Basel)
; 10(2)2021 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33546175
5.
Design, synthesis and SAR of a novel series of benzimidazoles as potent NPY Y5 antagonists.
Bioorg Med Chem Lett
; 20(23): 7120-3, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20951033
6.
Synthesis and structure-activity relationship of N-(3-azabicyclo[3.1.0]hex-6-ylmethyl)-5-(2-pyridinyl)-1,3-thiazol-2-amines derivatives as NPY Y5 antagonists.
Bioorg Med Chem Lett
; 20(16): 4741-4, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20630754
7.
The identification of a series of novel, soluble non-peptidic neuropeptide Y Y2 receptor antagonists.
Bioorg Med Chem Lett
; 20(24): 7341-4, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21074426
8.
Discovery and structure-activity relationship of a novel spirocarbamate series of NPY Y5 antagonists.
Bioorg Med Chem Lett
; 20(20): 6103-7, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20813523
9.
Gene expression signature of antidepressant treatment response/non-response in Flinders Sensitive Line rats subjected to maternal separation.
Eur Neuropsychopharmacol
; 31: 69-85, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31813757
10.
Selective Inhibitors of G2019S-LRRK2 Kinase Activity.
J Med Chem
; 63(23): 14821-14839, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33197196
11.
Evaluation of expression and function of the H+/myo-inositol transporter HMIT.
BMC Cell Biol
; 10: 54, 2009 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19607714
12.
The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists.
Bioorg Med Chem Lett
; 19(15): 4022-5, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19581086
13.
Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases.
Sci Rep
; 9(1): 3965, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850634
14.
Chronic stress-induced alterations in amygdala responsiveness and behavior--modulation by trait anxiety and corticotropin-releasing factor systems.
Eur J Neurosci
; 28(9): 1836-48, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18973598
15.
Acute stress differentially affects corticotropin-releasing hormone mRNA expression in the central amygdala of the "depressed" flinders sensitive line and the control flinders resistant line rats.
Prog Neuropsychopharmacol Biol Psychiatry
; 32(3): 651-61, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18077069
16.
Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy.
PLoS One
; 13(3): e0194225, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29529088
17.
Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression.
Neuropsychopharmacology
; 43(10): 2134-2145, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29950584
18.
Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y(1) receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression.
Eur Neuropsychopharmacol
; 17(4): 298-308, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16904299
19.
Nutrition for the ageing brain: Towards evidence for an optimal diet.
Ageing Res Rev
; 35: 222-240, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27713095
20.
Anxiolytic-like effect of the selective neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze.
Peptides
; 27(12): 3202-7, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16959374