Detalhe da pesquisa
1.
Dendritic cells direct circadian anti-tumour immune responses.
Nature
; 614(7946): 136-143, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36470303
2.
Fasting-mimicking diet and hormone therapy induce breast cancer regression.
Nature
; 583(7817): 620-624, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669709
3.
Inhibitors of NAD+ Production in Cancer Treatment: State of the Art and Perspectives.
Int J Mol Sci
; 25(4)2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396769
4.
Frailty assessment, hip fracture and long-term clinical outcomes in older adults.
Eur J Clin Invest
; 51(4): e13445, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33131066
5.
Author Correction: Fasting-mimicking diet and hormone therapy induce breast cancer regression.
Nature
; 588(7839): E33, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33273708
6.
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
FASEB J
; 33(3): 3704-3717, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514106
7.
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.
Mol Divers
; 24(3): 655-671, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31240519
8.
Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model.
FASEB J
; 31(7): 3138-3149, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28386046
9.
Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors.
Bioorg Med Chem Lett
; 26(13): 3192-3194, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27161804
10.
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity.
J Biol Chem
; 289(49): 34189-204, 2014 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25331943
11.
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.
BMC Cancer
; 15: 855, 2015 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26542945
12.
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.
J Biol Chem
; 288(36): 25938-25949, 2013 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23880765
13.
New Analogues of the Nicotinamide Phosphoribosyltransferase Inhibitor FK866 as Potential Anti-Pancreatic Cancer Agents.
Med Chem
; 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38333979
14.
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.
J Biol Chem
; 287(49): 40924-37, 2012 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23086953
15.
Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents.
Pharmaceutics
; 15(5)2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242714
16.
Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer.
Eur J Med Chem
; 250: 115170, 2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787658
17.
Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells.
Neoplasia
; 41: 100903, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37148658
18.
Cyclic fasting bolsters cholesterol biosynthesis inhibitors' anticancer activity.
Nat Commun
; 14(1): 6951, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37907500
19.
Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery.
Pharmaceuticals (Basel)
; 15(7)2022 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890147
20.
Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors.
Pharmaceuticals (Basel)
; 15(7)2022 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890155