Detalhe da pesquisa
1.
Inhibitors of ADAM10 reduce Hodgkin lymphoma cell growth in 3D microenvironments and enhance brentuximab-vedotin effect.
Haematologica
; 107(4): 909-920, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34109776
2.
Resveratrol-like Compounds as SIRT1 Activators.
Int J Mol Sci
; 23(23)2022 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499460
3.
Multifunctional Small Molecules as Potential Anti-Alzheimer's Disease Agents.
Molecules
; 26(19)2021 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641559
4.
Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis.
Bioorg Med Chem
; 28(18): 115673, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32828431
5.
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).
Bioorg Med Chem
; 27(1): 196-207, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30522899
6.
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates.
Bioorg Med Chem
; 26(22): 5804-5815, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429099
7.
MMP-8 Is Critical for Dexamethasone Therapy in Alkali-Burned Corneas Under Dry Eye Conditions.
J Cell Physiol
; 231(11): 2506-16, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26923552
8.
From Waste Vegetable Oil to a Green Compatibilizer for HDPE/PA6 Blends.
Polymers (Basel)
; 15(20)2023 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896422
9.
New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer's Disease.
Pharmaceutics
; 15(10)2023 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896129
10.
The Ca2+-ATPase (SERCA1) is inhibited by 4-aminoquinoline derivatives through interference with catalytic activation by Ca2+, whereas the ATPase E2 state remains functional.
J Biol Chem
; 286(44): 38383-38389, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21914795
11.
Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors.
ACS Med Chem Lett
; 12(11): 1787-1793, 2021 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35111280
12.
Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration.
ACS Chem Neurosci
; 11(20): 3214-3232, 2020 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32991141
13.
Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.
Cells
; 9(7)2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645949
14.
Development of antitubercular compounds based on a 4-quinolylhydrazone scaffold. Further structure-activity relationship studies.
Bioorg Med Chem
; 17(16): 6063-72, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19620006
15.
ADAM Metalloproteinases as Potential Drug Targets.
Curr Med Chem
; 26(15): 2661-2689, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-29589526
16.
Matrix metalloproteinase inhibitors prevent the release and proteolytic activity of monocyte/macrophage-derived microparticles.
Pharmacol Rep
; 71(3): 485-490, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31005034
17.
Design and Synthesis of Ionic Liquid-Based Matrix Metalloproteinase Inhibitors (MMPIs): A Simple Approach to Increase Hydrophilicity and to Develop MMPI-Coated Gold Nanoparticles.
ChemMedChem
; 14(6): 686-698, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30600908
18.
Synthesis and in vitro Evaluation of ADAM10 and ADAM17 Highly Selective Bioimaging Probes.
ChemMedChem
; 13(19): 2119-2131, 2018 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30102846
19.
Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells.
Oncoimmunology
; 7(5): e1421889, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29721369
20.
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.
J Med Chem
; 61(10): 4421-4435, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29727184