Detalhe da pesquisa
1.
SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D2 Receptor Mechanism of Action.
J Pharmacol Exp Ther
; 371(1): 1-14, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371483
2.
Discovery of 1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine, a dual serotonin and dopamine reuptake inhibitor.
Bioorg Med Chem Lett
; 21(1): 520-3, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21095126
3.
Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor.
Bioorg Med Chem Lett
; 21(5): 1438-41, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21310609
4.
Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor.
Bioorg Med Chem Lett
; 21(5): 1434-7, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21310612
5.
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Bioorg Med Chem
; 19(1): 663-76, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21093273
6.
Metabotropic glutamate receptors: potential drug targets for the treatment of schizophrenia.
Curr Drug Targets CNS Neurol Disord
; 1(3): 261-81, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12769619
7.
Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge.
Neuropsychopharmacology
; 28(9): 1622-32, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12825094
8.
Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor.
J Med Chem
; 47(18): 4595-9, 2004 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15317469
9.
Intravenous cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: phenotype and sex differences.
Psychopharmacology (Berl)
; 161(3): 304-13, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12021834
10.
The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats.
Psychopharmacology (Berl)
; 175(3): 310-8, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15024550
11.
Sex differences in the effects of baclofen on the acquisition of intravenous cocaine self-administration in rats.
Drug Alcohol Depend
; 66(1): 61-9, 2002 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11850137
12.
Effects of agmatine on the escalation of intravenous cocaine and fentanyl self-administration in rats.
Pharmacol Biochem Behav
; 72(4): 873-80, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12062577
13.
Effects of GABA modulators on the repeated acquisition of response sequences in squirrel monkeys.
J Exp Anal Behav
; 82(1): 37-56, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15484870
14.
Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo.
Pharmacol Res Perspect
; 1(1): e00007, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505561
15.
Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues.
J Med Chem
; 54(15): 5283-95, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21739935
16.
Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators.
Bioorg Med Chem Lett
; 15(6): 1565-71, 2005 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15745798
17.
Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): efficacy in an animal model for schizophrenia.
Bioorg Med Chem Lett
; 15(18): 4068-72, 2005 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16005222
18.
Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents.
J Pharmacol Exp Ther
; 306(1): 116-23, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12660307