Detalhe da pesquisa
1.
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Drug Metab Dispos
; 40(12): 2332-41, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961681
2.
Discovery of P2X3 selective antagonists for the treatment of chronic pain.
Bioorg Med Chem Lett
; 22(7): 2565-71, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22370269
3.
Development of a computational tool to rival experts in the prediction of sites of metabolism of xenobiotics by p450s.
J Chem Inf Model
; 52(9): 2471-83, 2012 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22916680
4.
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors.
J Med Chem
; 46(10): 1831-44, 2003 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-12723947
5.
Total Synthesis and Absolute Configuration of (-)-Anthoplalone.
J Org Chem
; 64(13): 4893-4900, 1999 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-11674567
6.
Evaluating MISER chromatography for a rapid formulation screen.
J Pharm Biomed Anal
; 77: 94-9, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23411002
7.
Virtual screening and computational optimization for the discovery of covalent prolyl oligopeptidase inhibitors with activity in human cells.
J Med Chem
; 55(14): 6306-15, 2012 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22765237
8.
Indanylacetic acid derivatives carrying aryl-pyridyl and aryl-pyrimidinyl tail groups--new classes of PPAR gamma/delta and PPAR alpha/gamma/delta agonists.
Bioorg Med Chem Lett
; 17(4): 1056-61, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17157013
9.
PDE-10A inhibitors as insulin secretagogues.
Bioorg Med Chem Lett
; 17(10): 2869-73, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17400452
10.
Indanylacetic acids as PPAR-delta activator insulin sensitizers.
Bioorg Med Chem Lett
; 17(15): 4369-73, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17601734
11.
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.
Bioorg Med Chem Lett
; 16(4): 859-63, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16298527