Detalhe da pesquisa
1.
Exploiting replication gaps for cancer therapy.
Mol Cell
; 82(13): 2363-2369, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568026
2.
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Mol Cell
; 81(15): 3128-3144.e7, 2021 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216544
3.
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Mol Cell
; 81(15): 3227, 2021 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358459
4.
RTEL1 maintains genomic stability by suppressing homologous recombination.
Cell
; 135(2): 261-71, 2008 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-18957201
5.
Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.
Genes Dev
; 29(5): 489-94, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737278
6.
Replication fork stability confers chemoresistance in BRCA-deficient cells.
Nature
; 535(7612): 382-7, 2016 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27443740
7.
FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links.
Nucleic Acids Res
; 48(16): 9161-9180, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32797166
8.
Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.
EMBO J
; 33(15): 1698-712, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24966277
9.
Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.
Nature
; 539(7629): 456, 2016 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27680696
10.
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome.
EMBO J
; 30(4): 692-705, 2011 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21240188
11.
FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response.
PLoS Genet
; 8(7): e1002786, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22792074
12.
FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells.
bioRxiv
; 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260529
13.
FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells.
Nat Commun
; 15(1): 2599, 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38521768
14.
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.
Cancer Cell
; 8(3): 255-65, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16153896
15.
Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1.
Future Oncol
; 7(2): 253-61, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21345144
16.
Revisiting the BRCA-pathway through the lens of replication gap suppression: "Gaps determine therapy response in BRCA mutant cancer".
DNA Repair (Amst)
; 107: 103209, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34419699
17.
Targeting translesion synthesis (TLS) to expose replication gaps, a unique cancer vulnerability.
Expert Opin Ther Targets
; 25(1): 27-36, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33416413
18.
Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1.
Mol Cancer Res
; 19(6): 1015-1025, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619228
19.
Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling.
Nat Commun
; 12(1): 2525, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33953191
20.
Replication Gaps Underlie BRCA Deficiency and Therapy Response.
Cancer Res
; 81(5): 1388-1397, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184108