Detalhe da pesquisa
1.
Genetic associations of protein-coding variants in human disease.
Nature
; 603(7899): 95-102, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197637
2.
Arrhythmias and ion channelopathies causing sudden cardiac death in Hispanic/Latino and Indigenous populations.
J Cardiovasc Electrophysiol
; 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38654386
3.
Identification of Cx43 variants predisposing to ventricular fibrillation in the acute phase of ST-elevation myocardial infarction.
Europace
; 25(1): 101-111, 2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35942675
4.
Antisense oligonucleotides as a potential treatment for brain deficits observed in myotonic dystrophy type 1.
Gene Ther
; 29(12): 698-709, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35075265
5.
SCN2A-related epilepsy of infancy with migrating focal seizures: report of a variant with apparent gain- and loss-of-function effects.
J Neurophysiol
; 127(5): 1388-1397, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417276
6.
Recent Progress and Challenges in the Development of Antisense Therapies for Myotonic Dystrophy Type 1.
Int J Mol Sci
; 23(21)2022 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36362145
7.
R1617Q epilepsy mutation slows NaV 1.6 sodium channel inactivation and increases the persistent current and neuronal firing.
J Physiol
; 599(5): 1651-1664, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33442870
8.
Deciphering the mechanisms underlying brain alterations and cognitive impairment in congenital myotonic dystrophy.
Neurobiol Dis
; 160: 105532, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34655747
9.
The myocardial and neuronal infectivity of SARS-CoV-2 and detrimental outcomes.
Can J Physiol Pharmacol
; 99(11): 1128-1136, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34546143
10.
Differentiation of lymphoblastoid-derived iPSCs into functional cardiomyocytes, neurons and myoblasts.
Biochem Biophys Res Commun
; 516(1): 222-228, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31208718
11.
Biophysical characterization of the Varroa destructor NaV1 sodium channel and its affinity for τ-fluvalinate insecticide.
FASEB J
; 31(7): 3066-3071, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356346
12.
Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C.
Handb Exp Pharmacol
; 246: 161-184, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29032483
13.
Induced pluripotent stem-cell-derived cardiomyocytes: cardiac applications, opportunities, and challenges.
Can J Physiol Pharmacol
; 95(10): 1108-1116, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28350968
14.
Molecular biology and biophysical properties of ion channel gating pores.
Q Rev Biophys
; 47(4): 364-88, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25382261
15.
Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea-pigs.
J Physiol
; 594(21): 6175-6187, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27296897
16.
Pathogenesis of the Novel Autoimmune-Associated Long-QT Syndrome.
Circulation
; 132(4): 230-40, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995318
17.
Unmasked Brugada pattern by ajmaline challenge in patients with myotonic dystrophy type 1.
Ann Noninvasive Electrocardiol
; 20(1): 28-36, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24943134
18.
Gating pore currents and the resting state of Nav1.4 voltage sensor domains.
Proc Natl Acad Sci U S A
; 109(47): 19250-5, 2012 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23134726
19.
Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics.
Mol Pharmacol
; 86(4): 378-89, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25028482
20.
Pyridoxal-5'-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors.
Can J Physiol Pharmacol
; 92(3): 189-96, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24593783