Detalhe da pesquisa
1.
Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
Cell
; 184(2): 384-403.e21, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450205
2.
Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis.
Proc Natl Acad Sci U S A
; 119(13): e2023784119, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35333654
3.
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426525
4.
Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles.
Chemistry
; 29(55): e202301888, 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37462979
5.
A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines.
Molecules
; 27(11)2022 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35684357
6.
Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library.
Bioorg Med Chem
; 48: 116387, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571488
7.
Practical and scalable synthesis of orthogonally protected-2-substituted chiral piperazines.
Org Biomol Chem
; 18(43): 8844-8849, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33118584
8.
Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production.
J Org Chem
; 84(10): 6040-6064, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30848904
9.
Synthesis of Enantiomerically Pure 3-Substituted Piperazine-2-acetic Acid Esters as Intermediates for Library Production.
J Org Chem
; 83(19): 11777-11793, 2018 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30180575
10.
Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production.
J Org Chem
; 83(12): 6541-6555, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29751727
11.
Correction to Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production.
J Org Chem
; 84(7): 4575, 2019 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30855144
12.
Expanding Complex Morpholines Using Systematic Chemical Diversity.
Org Lett
; 26(17): 3493-3497, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38506470
13.
Exploiting the Carboxylate-Binding Pocket of ß-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.
J Med Chem
; 67(1): 620-642, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117688
14.
Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1.
ACS Med Chem Lett
; 15(1): 107-115, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229743
15.
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors.
Commun Chem
; 6(1): 164, 2023 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37542196
16.
Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells.
mBio
; 13(3): e0078422, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35471084
17.
Small molecule modulators of protein-protein interactions: selected case studies.
Chem Rev
; 114(9): 4640-94, 2014 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24673632
18.
Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls.
ACS Comb Sci
; 22(12): 833-843, 2020 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074645
19.
Trisubstituted triumph.
Nat Chem
; 14(6): 595-597, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35668207
20.
Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons.
Eur J Med Chem
; 135: 110-116, 2017 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28441579