Diversity of daily activities is associated with greater hippocampal volume.

Greater engagement in a range of daily activities is associated with better cognitive functioning (Lee et al., Lee et al., 2020). The hippocampus, a subcortical brain structure implicated in learning, memory, spatial navigation and other aspects of cognitive functioning, may be structurally sensitive to exposure to and engagement with novel experiences and environments. The present study tested whether greater activity diversity, defined as the range of common daily activities engaged in and the proportion of time spent in each, is associated with larger hippocampal volume. Greater diversity of activities, as measured using daily diaries across an 8-day period, was related to greater hippocampal volume averaged across the left and right hemispheres, even when adjusting for estimated intracranial volume, total activity time, sociodemographic factors, and self-reported physical health. These findings are broadly consistent with nonhuman animal studies, demonstrating a link between enriched environments and structural changes to the hippocampus. Future longitudinal and experimental work can elucidate causal and directional relationships between diversity of daily activities and hippocampal volume.

Adding Insult to Injury: Everyday Discrimination Moderates Stressor-Related Negative Affect.

Studies examining the effects of discrimination on emotional well-being have often overlooked (a) differential effects of both everyday and lifetime discrimination and (b) how both types of discrimination may exacerbate stressor-related affect-even when daily stressors are unrelated to discrimination. The current study examined the effects of daily stressors not attributed to discrimination (i.e., nondiscrimination-related daily stressors) on daily negative and positive affect in the presence of either form of discrimination (everyday and lifetime). Participants who completed the second wave of the Survey of Midlife Development in the US (MIDUS-II) and the National Study of Daily Experiences (NSDE-II) answered questionnaires about everyday and lifetime discrimination. Later, they completed daily phone interviews across 8 consecutive days, asking about the nondiscrimination-related daily stressors and the positive and negative affect they had experienced that day. Multilevel model analyses revealed that everyday discrimination was associated with decreased daily positive affect and lifetime discrimination was associated with increased daily negative affect. Moreover, higher frequency of everyday discrimination exacerbated the within-person effects of nondiscriminatory daily stressors on negative affect. Results underscore the importance of considering both independent and synergistic effects of discrimination on daily emotional well-being.

The positive influence of sense of control on physical, behavioral, and psychosocial health in older adults: An outcome-wide approach.

Accumulating research indicates robust associations between sense of control and salutary health and well-being outcomes. However, whether change in sense of control is associated with subsequent outcomes has been under-evaluated. Participants (N = 12,998) were from the Health and Retirement Study-a diverse, nationally representative, and longitudinal sample of U.S. adults aged >50 years. We examined how increase in sense of control (from t0:2006/2008 to t1: 2010/2012) was associated with better outcomes on 35 indicators of: physical-, behavioral-, and psychosocial-health (t2:2014/2016). We used multiple logistic-, linear-, and generalized-linear regression models and controlled for sociodemographic characteristics, personality traits, sense of control, and all outcomes in the pre-baseline wave (t0:2006/2008). During the 4-year follow-up, people in the highest (vs. lowest) quartile of sense of control, conditional on prior sense of control, had reduced risk of mortality and improved physical-health outcomes (lower risk of: stroke, lung disease, physical limitations, cognitive impairment, chronic pain and higher self-rated health). Sense of control was related to better health-behaviors (increased physical activity, reduced sleep problems), higher psychological well-being (positive affect, life satisfaction, optimism, purpose, personal-, health-, financial-mastery), lower psychological distress (depression, hopelessness, negative affect, perceived constraints), decreased loneliness, and increased contact with friends. Sense of control was unrelated to other physical health indicators (diabetes, hypertension, heart disease, cancer, arthritis, overweight/obesity), health behaviors (binge drinking, smoking), and social factors (living with spouse/partner, frequency of contact with children and other family). These findings underscore the importance of sense of control as a potential intervention target for fostering physical-, behavioral-, and psychosocial-health.

National Institutes of Health Pathways to Prevention Workshop: Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention.

On 30 and 31 October 2018, the National Institutes of Health convened the Pathways to Prevention (P2P) Workshop: Appropriate Use of Drug Therapies for Osteoporotic Fracture Prevention to assess the available evidence on long-term (>3 years) use of drug therapies to prevent osteoporotic fractures and identify research gaps and needs for advancing the field. The workshop was cosponsored by the NIH Office of Disease Prevention (ODP), National Institute of Arthritis and Musculoskeletal and Skin Diseases, and National Institute on Aging. A multidisciplinary working group developed the agenda, and an Evidence-based Practice Center prepared an evidence report through a contract with the Agency for Healthcare Research and Quality to facilitate the discussion. During the 1.5-day workshop, invited experts discussed the body of evidence and attendees had the opportunity to comment during open discussions. After data from the evidence report, expert presentations, and public comments were weighed, an unbiased independent panel prepared a draft report that was posted on the ODP Web site for 5 weeks for public comment. This final report summarizes the panel's findings and recommendations. Current gaps in knowledge are highlighted, and a set of recommendations for new, strengthened research to better inform the long-term use of osteoporotic drug therapies is delineated.

Cultural differences in coping with interpersonal tensions lead to divergent shorter- and longer-term affective consequences.

Culture influences how people cope with interpersonal tensions, with those from more collectivistic contexts (e.g. Chinese Americans (CA)) generally opting for strategies promoting social harmony whereas those from more individualistic contexts (e.g. European Americans (EA)) preferring confrontational strategies. The current study examined cultural differences in coping strategy choices and their linkages to immediate affective reactions and subsequent affective memories. Participants (N = 159) discussed hypothetical dilemmas with a disagreeable confederate matched by age group, gender, and cultural group. CA exhibited less positive affect reactivity (i.e. smaller decreases in positive affect) and greater positive affect recovery (i.e. greater increases in post-task positive affect) compared to EA, which was explained by CAs' appraisals of greater emotional support from the confederate and lower endorsement of defending one's opinions. In contrast, one week later, EA, but not CA, recalled experiencing more task positive affect and less task negative affect than originally reported. Cultural differences in negative affect memory discrepancies were explained by EAs' greater tendency to defend their opinions, relative to CA. Culture shapes coping choices, which predict affective consequences over different time scales.

Let It Go: Lingering Negative Affect in Response to Daily Stressors Is Associated With Physical Health Years Later.

The way we respond to life's daily stressors has strong implications for our physical health. Researchers have documented the detrimental effects of initial emotional reactivity to daily stressors on future physical health outcomes but have yet to examine the effects of emotions that linger after a stressor occurs. The current study investigated how negative affect that lingers the day after a minor stressor occurs is associated with health-related outcomes. Participants ( N = 1,155) in a community-based, nationwide study answered questions about daily stressors and affect across 8 consecutive days and about their physical health almost 10 years later. Multilevel models indicated that people experience heightened levels of negative affect the day after a stressor occurs. Furthermore, higher levels of lingering negative affect are associated with greater numbers of chronic conditions and worse functional limitations 10 years later. Findings suggest that affective recovery from daily stressors has unique importance for long-term physical health.

Symptom Severity and Quality of Life Among Long-term Colorectal Cancer Survivors Compared With Matched Control Subjects: A Population-Based Study.

BACKGROUND: Data are lacking regarding physical functioning, psychological well-being, and quality of life among colorectal cancer survivors >10 years postdiagnosis. OBJECTIVE: The purpose of this study was to examine self-reported physical functioning, quality of life, and psychological well-being in long-term colorectal cancer survivors compared with age- and sex-matched unaffected control subjects. DESIGN: Participants completed a cross-sectional survey. SETTINGS: The colorectal cancer survivors and unaffected control subjects were recruited from the Ontario Familial Colorectal Cancer Registry. PATIENTS: A population-based sample of colorectal cancer survivors (N = 296) and their age- and sex-matched unaffected control subjects (N = 255) were included. Survivors were, on average, 15 years postdiagnosis. MAIN OUTCOME MEASURES: Quality of life was measured with the Functional Assessment of Cancer Therapy-General scale, bowel dysfunction with the Memorial Sloan-Kettering Cancer Center scale, urinary dysfunction with the International Consultation on Incontinence Questionnaire-Short Form, fatigue with the Functional Assessment of Chronic Illness Therapy-Fatigue scale, and depression with the Center for Epidemiologic Studies-Depression scale. RESULTS: In linear mixed-model analyses adjusting for income, education, race, and comorbid medical conditions, survivors reported good emotional, functional, physical, and overall quality of life, comparable to control subjects. Fatigue and urinary functioning did not differ significantly between survivors and control subjects. Survivors reported significantly higher social quality of life and lower depression compared with unaffected control subjects. The only area where survivors reported significantly worse deficits was in bowel dysfunction, but the magnitude of differences was relatively small. LIMITATIONS: Generalizability is limited by moderately low participation rates. Findings are likely biased toward healthy participants. No baseline assessment was available to examine change in outcomes over time. CONCLUSIONS: Long-term colorectal cancer survivors appear to have comparable quality of life and, in some areas, better well-being than their unaffected peers. Bowel dysfunction may continue to be an ongoing issue even 15 years after colorectal cancer diagnosis. Overall quality of life can be expected to be good in this group of older survivors. See Video Abstract at http://links.lww.com/DCR/A476.

Neighborhood Socioeconomic Status and Health: A Longitudinal Analysis.

Higher income neighborhoods are associated with better health, a relation observed in many cross-sectional studies. However, prior research focused on the prevalence of health conditions, and examining the incidence of new health conditions may provide stronger support for a potential causal role of neighborhoods on health. We used the 2004 and 2014 waves of the Midlife in the United States Study (n = 1726; ages 34-83) to examine health condition incidence as a function of neighborhood income. Among participants who had lived in the same neighborhood across the time period, we hypothesized that higher neighborhood income would be associated with a lower incidence of health conditions ten years later. Health included 18 chronic conditions related to mental (anxiety, depression) and physical (cardiovascular, immune) health. Multinomial logistic regression analyses adjusting for individual income and sociodemographics indicated that the odds of developing two or more new health conditions (no new health conditions as referent), was significantly lower (OR = 0.92, CI: 0.86, 0.99) for every $10,000 increment in neighborhood income. Associations did not vary by age or neighborhood tenure. Results add to a literature documenting that higher neighborhood income is associated with better health.

Looking back, forging ahead: Fifteen years of Strength and Vulnerability Integration (SAVI).

Strength and Vulnerability Integration (SAVI) describes age-related patterns of emotional well-being. Since its initial publication, studies have tested the model, supporting its original tenets and also identifying areas needing refinement. The current review provides an updated description of SAVI, describing how age differences in well-being vary based on the proximity to acute stressors and the proposed underlying mechanisms. SAVI also addresses questions regarding why we sometimes observe increases in distress among older adults over time. In this description, we clarify predictions of SAVI, as well as suggest places where more research is needed.

A Greater Variety of Social Activities Is Associated With Lower Mortality Risk.

OBJECTIVES: More frequent engagement in social activity is often associated with better physical health outcomes. Yet, less is known about whether engagement in a greater variety of social activities such as a mix of volunteering and attending club meetings (social activity variety) is important for health. The current study assessed whether social activity variety relates to mortality risk after adjusting for social activity frequency, nonsocial activity frequency and variety, and sociodemographic covariates, and how this relationship varies depending on age. METHODS: Using data from the Health and Retirement Study, we included 5,017 adults aged 51 and older who completed questions about social activity participation in 2008 and whose mortality status was recorded up to 2019. We also examined whether age moderated the relationship between social activity variety and mortality risk. RESULTS: Cox proportional hazard model analyses revealed that those with higher activity variety in social activities were more likely to survive over the following 11 years than those with low social activity variety. Moreover, age moderation indicated that the association between social activity variety with mortality risk was stronger among the oldest adults. DISCUSSION: Findings suggest that a greater variety of social activities is linked to mortality risk even after adjusting for social activity frequency, nonsocial activities, and health status across adulthood.

Too little, too much, and "just right": Exploring the "goldilocks zone" of daily stress reactivity.

Hormetic models of stress resilience describe nonlinear relations for exposure to adversity and health outcomes, where exposure induces salutary changes up to a threshold, with changes becoming deleterious afterward. Here we apply a hormetic model of stress to reactivity to daily stressors, examining whether mental and physical health benefits arise from low-to-moderate reactivity but then decrease at higher levels. Data are from the second wave of the National Study of Daily Experiences (NSDE). Adults (N = 2,022; Mage = 58.61, SD = 12.12, age range: 35-86; 57% female) completed telephone interviews detailing their stressors and affect on eight consecutive evenings. A series of multilevel structural equation models estimated within-person associations between daily stressors and negative affect (i.e., stress reactivity), and between-person linear and quadratic effects of stress reactivity on mental and physical health outcomes (i.e., life satisfaction, psychological distress, and number of chronic conditions). Findings reveal a significant quadratic effect for each outcome, indicating a U-shaped pattern (inverse U for positively valenced life satisfaction), such that low and high levels of stress reactivity were associated with poorer health and well-being, whereas moderate levels of daily stress reactivity predicted better health outcomes. These findings suggest that individuals who display either very low- or very high-stress reactivity may benefit from interventions that target their emotion regulation skills and coping resources. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Perceived control across the adult lifespan: Longitudinal changes in global control and daily stressor control.

Perceived control is an important psychosocial resource for health and well-being across the lifespan. Global control (i.e., overall perceived control) decreases over time in studies following people every few years to upwards of 10 years. Changes across wider intervals of the lifespan, however, have yet to be examined. Further, how perceived control changes for specific aspects of daily life, such as stressors, remains comparatively less clear. Using data from the Midlife in the United States National Study of Daily Experiences (NSDE, N = 1,940, M = 56.25 years, SD = 12.20, 57% female), we examined longitudinal changes in global control across 20 years and daily stressor control across 10 years. Global control was assessed in the first wave of the NSDE (∼1996). In follow-up waves, conducted in ∼2008 and ∼2017, participants again not only reported their global control but also reported their perceived control over stressors they experience across 8 consecutive days. Longitudinal analyses revealed differential change trajectories for global control across 20 years and stressor control across 10 years (ps < .001). Global control declined for younger and older adults but stayed relatively stable for individuals in midlife. The rate of decline in daily stressor control was steeper than the decline in global control and did not vary by age at baseline. In addition, declines were amplified among individuals with higher global control at baseline. Results suggest that daily stressor control is a specific aspect of control beliefs that follows a different rate of change than global control. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Preserving What Matters: Longitudinal Changes in Control Over Interpersonal Stress and Noninterpersonal Stress in Daily Life.

OBJECTIVES: Theoretical perspectives on aging suggest that when people experience declines in later life, they often selectively focus on maintaining aspects of their lives that are most meaningful and important to them. The social domain is one of these selected areas. The current study examines people's reports of control over their daily stressors over 10 years, predicting that the declines in control that are often observed in later life will not be observed for stressors involving interpersonal conflict and tensions with social partners. METHODS: Adults ranging from 35 to 86 years old at baseline (N = 1,940), from the National Study of Daily Experiences, reported control over interpersonal and noninterpersonal daily stressors across 8 consecutive days at 2 time points, about 10 years apart. RESULTS: Findings from multilevel models indicate that for noninterpersonal stressors, perceived control decreased over time. In contrast, perceived control over interpersonal conflicts and tensions remained robust over time. No cross-sectional baseline age differences were found for levels of interpersonal and noninterpersonal stressor control. DISCUSSION: Results are consistent with socioemotional selectivity and underscore the importance of interpersonal relationships in later adulthood. Understanding how people select and preserve certain aspects of control in their daily life can help guide efforts toward maximizing gains and minimizing losses in domains that matter most to people as they grow older.

The wear and tear of daily stressors on mental health.

Researchers assert that affective responses to seemingly minor daily events have long-term implications for mental health, yet this phenomenon has rarely been investigated. In the current study, we examined how levels of daily negative affect and affective reactivity in response to daily stressors predicted general affective distress and self-reported anxiety and depressive disorders 10 years after they were first assessed. Across eight consecutive evenings, participants (N = 711; age = 25 to 74 years) reported their daily stressors and their daily negative affect. Increased levels of negative affect on nonstressor days were related to general affective distress and symptoms of an affective disorder 10 years later. Heightened affective reactivity to daily stressors predicted greater general affective distress and an increased likelihood of reporting an affective disorder. These findings suggest that the average levels of negative affect that people experience and how they respond to seemingly minor events in their daily lives have long-term implications for their mental health.

Affective reactivity to daily stressors and long-term risk of reporting a chronic physical health condition.

BACKGROUND: Daily stressors, such as an argument with a spouse or an impending deadline, are associated with short-term changes in physical health symptoms. Whether these minor hassles have long-term physical health ramifications, however, is largely unknown. PURPOSE: The current study examined whether exposure and reactivity to daily stressors is associated with long-term risk of reporting a chronic physical health condition. METHODS: Participants (N = 435) from the National Study of Daily Experiences completed a series of daily diary interviews between 1995 and 1996 and again 10 years later. RESULTS: Greater affective (i.e., emotional) reactivity to daily stressors at time 1 was associated with an increased risk of reporting a chronic physical health condition at time 2. CONCLUSION: Results indicate that how people respond to the daily stressors in their lives is predictive of future chronic health conditions.

Physical Activity and Daily Stress Processes in Older Adulthood.

OBJECTIVES: Older adults who are physically active report lower levels of stress. Less is known about the links between physical activity and exposure and reactivity to stressful events in daily life. The current study examined within-person associations between actigraphy-assessed daily physical activity and exposure and affective reactivity to naturally occurring interpersonal stressors. METHOD: Older adults (N = 180) from the Daily Experiences and Well-being Study completed ecological momentary assessments (EMAs) every 3 hr for 5-6 days where they reported negative affect throughout the day and interpersonal tensions at the end of the day. They also wore Actical accelerometers to capture physical activity. RESULTS: Older adults reported greater numbers of interpersonal stressors on days when they spent less time being sedentary and engaged in more light physical activity. On days when older adults experienced more interpersonal stressors, they reported higher levels of negative affect, but this association was attenuated when they were more physically active that day. DISCUSSION: Physical activity may bolster older adults' capabilities to manage affective responses to interpersonal stressors in a more successful way. These findings underscore the importance of assessing physical activity and stressful events in daily life and have implications for both physical and psychological well-being.

Chronic Pain and Affective Experiences Associated with Daily Stressors and Uplifts.

People with chronic pain often report greater reactivity to stress than those without pain. This finding is consistent with the kindling hypothesis, which states that continued exposure to stressors only heightens negative affect and dampens positive affect. Yet, people with chronic pain may also respond more positively to enjoyable activities, or uplifts, as well. Chronic pain is related to lower levels of well-being, and the fragility of positive affect model explains how individuals with lower levels of well-being often exhibit stronger, more positive responses to daily uplifts than their less distressed peers. Our study used the National Study of Daily Experiences to assess daily stressors, positive uplifts, and positive and negative affect across eight days among those with and without chronic pain. Participants (nChronicPain=658, nNoPain=1,075) were predominately Non-Hispanic White (91%), 56% female, and averaged 56 years old. Results revealed that people with chronic pain had lower levels of daily positive affect and higher levels of negative affect, yet the two groups did not vary in their stressor-related negative and positive affect. In contrast, having chronic pain was related to a greater increase in positive affect and greater decreases in negative affect on days with positive uplifts. Findings suggest that intervention efforts focusing on uplifts may be particularly helpful for people who report chronic pain.

Growing old and being old: Emotional well-being across adulthood.

The present study examines change in reports of daily, weekly, and monthly psychological distress over 20 years, and of negative and positive affect over 10 years, using data from the Midlife in the United States study. The study includes three waves of data collection on adults ranging from 22 to 95 years old. Cross-sectional findings reveal that older age is related to lower levels of psychological distress and negative affect and to higher levels of positive affect across each successive age group. Yet, longitudinal findings vary across younger, middle-aged, and older adults. Psychological distress decreases over time among younger adults (although only until age 33 for weekly reports), remains stable in midlife, and is stable (monthly) or slightly increases (daily and weekly) among older adults. For negative affect, levels decrease over time for younger and middle-aged adults, and only increase for the oldest adults for daily and monthly affect. Positive affect is stable over time among younger adults, but decreases in midlife starting in the mid-fifties. In conclusion, overall patterns of findings suggest that being old (assessed cross-sectionally) is related to higher levels of emotional well-being. Growing old (assessed longitudinally) is related to improvements in emotional well-being across younger and early middle adulthood, which mirrors cross-sectional findings. There is relative stability in later midlife, however, and continued stability or slight declines across older age. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Switching it up: Activity diversity and cognitive functioning in later life.

Participating in a broad and balanced range of daily activities (i.e., activity diversity) has been associated with better cognitive functioning in later life. One possible explanation for this finding is that high levels of activity diversity are merely a proxy for being more physically active, a factor robustly linked to cognitive health. The present study examined whether activity diversity has a unique association with cognitive functioning beyond physical movement. Community-dwelling older adults (N = 252, Mage = 73.55 years, SD = 6.39) completed a cognitive battery and then responded to ecological momentary assessments of their participation in 10 common activity types (e.g., reading, chores, social visits) every 3 hr for 5-6 days. They also wore accelerometers to track daily physical movement. Multiple regression models revealed that greater diversity in daily activities was related to higher cognitive functioning even after adjusting for physical movement and other covariates such as education level. This study further clarifies the unique relationship of activity diversity, beyond physical movement, with cognition. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Who Has Active Lifestyles? Sociodemographic and Personality Correlates of Activity Diversity in Two Samples of Adults.

OBJECTIVES: Activity diversity-an index of active lifestyles that captures variety (number) and evenness (consistency) in activity engagement-is known to support health in adulthood. However, less is known who has higher or lower activity diversity, information that helps identify individuals who may be at greater risk for poor health. This article examined sociodemographic characteristics and Big Five personality traits that may be associated with activity diversity. METHODS: We used 2 independent project samples (nsample1 = 2,699; nsample2 = 301). Sample 1 included U.S. national adults in a wide age range (25-84). Sample 2 included U.S. community-dwelling older adults (age = 65-89). Each study asked about different types of activity engagement using surveys. The activity diversity index was calculated in each sample, using Shannon's entropy method. RESULTS: In Sample 1, older adults, women, non-Hispanic White individuals, married/partnered individuals, and those with higher education and fewer functional limitations had higher activity diversity. Additionally, higher conscientiousness, higher extraversion, and lower neuroticism were each associated with higher activity diversity after controlling for sociodemographic factors. Extraversion and neuroticism remained significant in the younger group (age < 65) of Sample 1, but only extraversion was a significant factor associated with activity diversity in the older group (age ≥ 65). The results in the older group were generally replicated in Sample 2, such that higher extraversion in older adults was consistently associated with higher activity diversity independent of the strong correlates of sex, education, and functional limitations. DISCUSSION: Findings were discussed in terms of age-specific associations between sociodemographic and personality characteristics and activity diversity.