Detalhe da pesquisa
1.
Akt Phosphorylation Orchestrates T11TS Mediated Cell Cycle Arrest in Glioma Cells.
Cancer Invest
; 39(10): 854-870, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34569407
2.
Low-Level Nanog Expression in the Regulation of Quiescent Endothelium.
Arterioscler Thromb Vasc Biol
; 40(9): 2244-2264, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32640900
3.
T11TS immunotherapy augments microglial and lymphocyte protective immune responses against Cryptococcus neoformans in the brain.
Scand J Immunol
; 89(2): e12733, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30450625
4.
The allosteric glycogen synthase kinase-3 inhibitor NP12 limits myocardial remodeling and promotes angiogenesis in an acute myocardial infarction model.
J Biol Chem
; 292(50): 20785-20798, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29070680
5.
T11TS immunotherapy repairs PI3K-AKT signaling in T-cells: Clues toward enhanced T-cell survival in rat glioma model.
J Cell Physiol
; 233(2): 759-770, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28608562
6.
T11TS Treatment Augments Apoptosis of Glioma Associated Brain Endothelial Cells, Hint Toward Anti-Angiogenic Action in Glioma.
J Cell Physiol
; 232(3): 526-539, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27255231
7.
T11TS inhibits Angiopoietin-1/Tie-2 signaling, EGFR activation and Raf/MEK/ERK pathway in brain endothelial cells restraining angiogenesis in glioma model.
Exp Mol Pathol
; 98(3): 455-66, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25797371
8.
T11TS inhibits glioma angiogenesis by modulation of MMPs, TIMPs, with related integrin αv and TGF-ß1 expressions.
Tumour Biol
; 35(3): 2231-46, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24242015
9.
The novel immunotherapeutic molecule T11TS modulates glioma-induced changes of key components of the immunological synapse in favor of T cell activation and glioma abrogation.
J Neurooncol
; 120(1): 19-31, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25026997
10.
Significant modulation of macrophages associated cytokines TNF-α, VEGF and apoptotoic protein Bax, Bcl2 abrogates tumor cells.
Cell Immunol
; 284(1-2): 172-81, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994239
11.
T11TS impedes glioma angiogenesis by inhibiting VEGF signaling and pro-survival PI3K/Akt/eNOS pathway with concomitant upregulation of PTEN in brain endothelial cells.
J Neurooncol
; 113(1): 13-25, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23471571
12.
Immunomodulatory role of TIITS in respect to cytotoxic lymphocytes in four grades of human glioma.
Cell Immunol
; 276(1-2): 176-86, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22704241
13.
Comparative evaluation of T11 target structure and its deglycosylated derivative nullifies the importance of glycan moieties in immunotherapeutic efficacy.
Acta Biochim Biophys Sin (Shanghai)
; 44(3): 259-68, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22257732
14.
Therapeutic intervention of glioma with the novel antineoplastic agent T11TS: the story so far.
Immunotherapy
; 14(15): 1263-1277, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36004447
15.
Induction of G1 arrest in glioma cells by T11TS is associated with upregulation of Cip1/Kip1 and concurrent downregulation of cyclin D (1 and 3).
Anticancer Drugs
; 21(1): 53-64, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19829098
16.
Regulation of key molecules of immunological synapse by T11TS immunotherapy abrogates Cryptococcus neoformans infection in rats.
Mol Immunol
; 122: 207-221, 2020 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32388483
17.
Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction.
Front Microbiol
; 8: 706, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28484443
18.
Specific allergen immunotherapy attenuates allergic airway inflammation in a rat model of Alstonia scholaris pollen induced airway allergy.
Int Immunopharmacol
; 30: 111-120, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26667977
19.
T11 target structure induced modulations of the pro-inflammatory and anti-infammatorycytokine expressions in experimental animals for glioma abrogation.
Int Immunopharmacol
; 24(2): 198-207, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25528475
20.
Disease relevance of T11TS-induced T-cell signal transduction through the CD2-mediated calcineurin-NFAT pathway: Perspectives in glioma immunotherapy.
Mol Immunol
; 67(2 Pt B): 256-64, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26105805