Detalhe da pesquisa
1.
Germline variation in RASAL2 may predict survival in patients with RAS-activated colorectal cancer.
Genes Chromosomes Cancer
; 62(6): 332-341, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790221
2.
Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome.
Int J Cancer
; 151(6): 957-966, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467766
3.
Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer.
Int J Cancer
; 149(9): 1713-1722, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270794
4.
Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis.
Br J Cancer
; 124(6): 1169-1174, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33414539
5.
Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab.
J Med Genet
; 54(8): 567-571, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283541
6.
Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis.
Carcinogenesis
; 37(1): 87-95, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586795
7.
Pan-Cancer Interrogation of MUTYH Variants Reveals Biallelic Inactivation and Defective Base Excision Repair Across a Spectrum of Solid Tumors.
JCO Precis Oncol
; 8: e2300251, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38394468
8.
Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer.
Hum Mutat
; 34(7): 1026-34, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23585368
9.
Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.
Nat Genet
; 30(2): 227-32, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11818965
10.
Relationship between 233 colorectal cancer risk loci and survival in 1926 patients with advanced disease.
BJC Rep
; 1(1): 2, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665548
11.
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial.
Lancet
; 377(9783): 2103-14, 2011 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21641636
12.
Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.
Hum Mol Genet
; 18(12): 2166-76, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19321600
13.
A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients.
Eur J Cancer
; 159: 247-258, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34794066
14.
Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants.
Eur J Cancer
; 124: 56-63, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31734605
15.
Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.
Lancet Gastroenterol Hepatol
; 5(1): 55-62, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668584
16.
The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations.
Hum Mutat
; 30(10): 1412-8, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19701947
17.
Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer.
J Natl Cancer Inst
; 111(8): 828-836, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30649440
18.
MUTYH-associated polyposis--from defect in base excision repair to clinical genetic testing.
DNA Repair (Amst)
; 6(3): 274-9, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17161978
19.
Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures.
Ann Neurol
; 62(6): 648-55, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18067135
20.
Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy.
Eur J Cancer
; 102: 31-39, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30114658