Detalhe da pesquisa
1.
A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.
Nat Immunol
; 14(5): 470-9, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23542741
2.
E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro.
J Biol Chem
; 299(12): 105388, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37890782
3.
F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation.
Nat Immunol
; 13(7): 651-8, 2012 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22660580
4.
Cross-Regulation of F-Box Protein FBXL2 with T-bet and TNF-α during Acute and Chronic Lung Allograft Rejection.
J Immunol
; 209(9): 1788-1795, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36113884
5.
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Nat Chem Biol
; 17(3): 298-306, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495648
6.
CD4+ T-Cell Dysfunction in Severe COVID-19 Disease Is Tumor Necrosis Factor-α/Tumor Necrosis Factor Receptor 1-Dependent.
Am J Respir Crit Care Med
; 205(12): 1403-1418, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35348444
7.
Fibronectin-EDA accumulates via reduced ubiquitination downstream of Toll-like receptor 9 activation in SSc-ILD fibroblasts.
Am J Physiol Lung Cell Mol Physiol
; 323(4): L484-L494, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35997276
8.
Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
J Biol Chem
; 295(13): 4171-4180, 2020 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071084
9.
SCF FBXW17 E3 ubiquitin ligase regulates FBXL19 stability and cell migration.
J Cell Biochem
; 122(3-4): 326-334, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33053230
10.
Toll-like Receptor 8 Stability Is Regulated by Ring Finger 216 in Response to Circulating MicroRNAs.
Am J Respir Cell Mol Biol
; 62(2): 157-167, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31385713
11.
The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing.
J Biol Chem
; 294(45): 16527-16534, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586034
12.
The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis.
J Mol Cell Cardiol
; 126: 50-59, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30448480
13.
Host-Response Subphenotypes Offer Prognostic Enrichment in Patients With or at Risk for Acute Respiratory Distress Syndrome.
Crit Care Med
; 47(12): 1724-1734, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31634231
14.
LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1.
J Cell Sci
; 129(1): 51-64, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26604221
15.
Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation.
FASEB J
; 31(9): 3894-3903, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28515150
16.
Post-translational modification of the interferon-gamma receptor alters its stability and signaling.
Biochem J
; 474(20): 3543-3557, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28883123
17.
RING finger protein 113A regulates C-X-C chemokine receptor type 4 stability and signaling.
Am J Physiol Cell Physiol
; 313(5): C584-C592, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28978524
18.
Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase.
J Biol Chem
; 290(29): 18124-18133, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26037928
19.
The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin.
J Biol Chem
; 290(19): 11843-52, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25778398
20.
Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.
J Biol Chem
; 290(27): 16861-72, 2015 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001785