Detalhe da pesquisa
1.
Tas2R activation relaxes airway smooth muscle by release of Gαt targeting on AChR signaling.
Proc Natl Acad Sci U S A
; 119(26): e2121513119, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35737832
2.
TMNP: a transcriptome-based multi-scale network pharmacology platform for herbal medicine.
Brief Bioinform
; 23(1)2022 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34933331
3.
Repositioning baloxavir marboxil as VISTA agonist that ameliorates experimental asthma.
Cell Biol Toxicol
; 40(1): 12, 2024 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38340268
4.
Recent advances in targeting leucine-rich repeat kinase 2 as a potential strategy for the treatment of Parkinson's disease.
Bioorg Chem
; 141: 106906, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37837728
5.
[Prenatal diagnosis and genetic analysis of a special case with complex structural rearrangements of chromosome 8].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
; 40(9): 1181-1184, 2023 Sep 10.
Artigo
em Zh
| MEDLINE | ID: mdl-37643970
6.
A Transposon-Associated CRISPR/Cas9 System Specifically Eliminates both Chromosomal and Plasmid-Borne mcr-1 in Escherichia coli.
Antimicrob Agents Chemother
; 65(10): e0105421, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34339270
7.
Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction.
J Chem Inf Model
; 61(10): 5269-5279, 2021 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34553597
8.
ISKpn40-Mediated Mobilization of the Colistin Resistance Gene mcr-3.11 in Escherichia coli.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660996
9.
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Clin Sci (Lond)
; 134(17): 2381-2398, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32880392
10.
ZIPK mediates endothelial cell contraction through myosin light chain phosphorylation and is required for ischemic-reperfusion injury.
FASEB J
; 33(8): 9062-9074, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31180722
11.
Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation.
J Chem Inf Model
; 60(6): 3255-3264, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32282203
12.
Decision aids on breast conserving surgery for early stage breast cancer patients: a systematic review.
BMC Med Inform Decis Mak
; 20(1): 275, 2020 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33092602
13.
Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma.
J Allergy Clin Immunol
; 141(4): 1259-1268.e11, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28754608
14.
Synthesis and biological evaluation of Complex I inhibitor R419 and its derivatives as anticancer agents in HepG2 cells.
Bioorg Med Chem Lett
; 28(17): 2957-2960, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30001917
15.
Regulation of DLK1 by the maternally expressed miR-379/miR-544 cluster may underlie callipyge polar overdominance inheritance.
Proc Natl Acad Sci U S A
; 112(44): 13627-32, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26487685
16.
Physiological vs. pharmacological signalling to myosin phosphorylation in airway smooth muscle.
J Physiol
; 595(19): 6231-6247, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28749013
17.
Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors.
Bioorg Med Chem Lett
; 27(4): 845-849, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28108249
18.
Physiological signalling to myosin phosphatase targeting subunit-1 phosphorylation in ileal smooth muscle.
J Physiol
; 594(12): 3209-25, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26847850
19.
In vivo roles for myosin phosphatase targeting subunit-1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction.
J Physiol
; 593(3): 681-700, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25433069
20.
Myosin light chain kinase (MLCK) regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism.
J Biol Chem
; 289(41): 28478-88, 2014 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122766