Detalhe da pesquisa
1.
Design, synthesis, biological evaluation and molecular dynamics simulation studies of imidazolidine-2,4-dione derivatives as novel PTP1B inhibitors.
Biochem Biophys Res Commun
; 579: 40-46, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34583194
2.
Design, synthesis, biological activity and molecular dynamics studies of specific protein tyrosine phosphatase 1B inhibitors over SHP-2.
Int J Mol Sci
; 14(6): 12661-74, 2013 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23774838
3.
Design, synthesis and evaluation of novel metalloproteinase inhibitors based on L-tyrosine scaffold.
Bioorg Med Chem
; 20(19): 5738-44, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22967811
4.
Exploring Dual Agonists for PPARα/γ Receptors using Pharmacophore Modeling, Docking Analysis and Molecule Dynamics Simulation.
Comb Chem High Throughput Screen
; 25(9): 1450-1461, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34182904
5.
Methyl 3,4-bis-(cyclo-propyl-meth-oxy)benzoate.
Acta Crystallogr Sect E Struct Rep Online
; 67(Pt 5): o1130, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21754441
6.
In-silico identification of peroxisome proliferator-activated receptor (PPAR)α/γ agonists from Ligand Expo Components database.
J Biomol Struct Dyn
; 39(5): 1853-1864, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32189570
7.
Three new powerful oseltamivir derivatives for inhibiting the neuraminidase of influenza virus.
Biochem Biophys Res Commun
; 401(2): 188-91, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20849817
8.
Mechanism of tetramethylpyrazine analogue CXC195 inhibition of hydrogen peroxide-induced apoptosis in human endothelial cells.
Biol Pharm Bull
; 33(3): 432-8, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20190405
9.
1-(4-Methoxy-phen-yl)imidazolidine-2,4-dione.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 6): o1308, 2010 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21579403
10.
Methyl 4-(cyclopropylmethoxy)-3-hydroxybenzoate [corrected].
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 8): o2004, 2010 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21588318
11.
3-Hy-droxy-methyl-1-(4-meth-oxy-phen-yl)imidazolidine-2,4-dione.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 8): o2027, 2010 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21588337
12.
3-Bromo-1-(3-chloro-pyridin-2-yl)-N-(4-eth-oxy-phen-yl)-1H-pyrazole-5-carbox-amide.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 11): o2961, 2010 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21589129
13.
Discovery of novel and highly selective PI3Kδ inhibitors based on the p110δ crystal structure.
J Biomol Struct Dyn
; 38(8): 2499-2508, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31232196
14.
Virtual identification of novel PPARα/γ dual agonists by 3D-QSAR, molecule docking and molecular dynamics studies.
J Biomol Struct Dyn
; 38(9): 2672-2685, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31418313
15.
Virtual identification of novel peroxisome proliferator-activated receptor (PPAR) α/δ dual antagonist by 3D-QSAR, molecule docking, and molecule dynamics simulation.
J Biomol Struct Dyn
; 38(14): 4143-4161, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31556349
16.
Ligustrazine derivatives. Part 3: Design, synthesis and evaluation of novel acylpiperazinyl derivatives as potential cerebrocardiac vascular agents.
Bioorg Med Chem
; 17(8): 3018-24, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19329327
17.
Identification of novel PPARα/γ dual agonists by pharmacophore screening, docking analysis, ADMET prediction and molecular dynamics simulations.
Comput Biol Chem
; 78: 178-189, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30557816
18.
Identification of novel PI3Kδ inhibitors by docking, ADMET prediction and molecular dynamics simulations.
Comput Biol Chem
; 78: 190-204, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30557817
19.
Role of sulfonamide group in matrix metalloproteinase inhibitors.
Curr Med Chem
; 15(4): 368-73, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18288991
20.
Advances in matrix metalloproteinase inhibitors based on pyrrolidine scaffold.
Curr Med Chem
; 15(4): 374-85, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18288992