Detalhe da pesquisa
1.
Automated synthesis of (R)-[18 F]MH.MZ on the iPhase Flexlab reaction platform.
J Labelled Comp Radiopharm
; 65(8): 223-229, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35491085
2.
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).
Bioorg Med Chem Lett
; 26(13): 2984-2987, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27234146
3.
Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.
Bioorg Med Chem Lett
; 24(18): 4466-4471, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172419
4.
Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes.
Tetrahedron Lett
; 55(1)2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24396154
5.
Fully automated dual-run manufacturing of [11C]PIB on FASTlab.
Nucl Med Biol
; 128-129: 108873, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38154168
6.
Synthesis and Evaluation of a Novel PET Radioligand for Imaging Glutaminyl Cyclase Activity as a Biomarker for Detecting Alzheimer's Disease.
ACS Sens
; 9(5): 2605-2613, 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38718161
7.
Fully automated radiosynthesis of [68Ga]Ga-FAPI-46 with cyclotron produced gallium.
EJNMMI Radiopharm Chem
; 8(1): 29, 2023 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37843670
8.
Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012.
Bioorg Med Chem Lett
; 22(15): 5035-40, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22749871
9.
Discovery, Synthesis, and Preclinical Characterization of N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4).
ACS Chem Neurosci
; 7(9): 1192-200, 2016 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27075300
10.
High-yielding, automated production of 3'-deoxy-3'-[(18)F]fluorothymidine using a modified Bioscan Coincidence FDG reaction module.
Appl Radiat Isot
; 97: 47-51, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25531913
11.
Acyl sulfonamide anti-proliferatives: benzene substituent structure-activity relationships for a novel class of antitumor agents.
J Med Chem
; 47(22): 5367-80, 2004 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15481975
12.
A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.
Clin Cancer Res
; 20(8): 2126-35, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24573549
13.
Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor.
J Med Chem
; 55(15): 6975-9, 2012 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22793372
14.
Solution-phase parallel synthesis and SAR of homopiperazinyl analogs as positive allosteric modulators of mGlu4.
ACS Comb Sci
; 13(2): 159-65, 2011 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21338051
15.
Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives.
Bioorg Med Chem Lett
; 15(3): 617-20, 2005 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15664824