Ultrasonographic quantitative evaluation of acute and chronic renal disease using the renal cortical thickness to aorta ratio in dogs.

The renal cortical thickness (RCT) has been correlated with renal function. Previous studies have also reported that the RCT:Abdominal aorta(Ao) ratio is constant in normal dogs with various physical factors. This multi-center, retrospective, analytical study aimed to determine if there are differences between actual RCT and predicted value of RCT considering physical factors in dogs with acute or chronic renal disease. We also aimed to demonstrate whether the RCT and Ao ratio index would be useful for evaluating renal pathology. A total of 54 dogs with acute or chronic renal disease and 30 normal healthy dogs were included in this study. The RCT was measured at the center of the renal pyramid as the shortest distance perpendicular to the renal capsule from the base of the renal medullary pyramid at three points. The diameter of the Ao was measured just caudal to the branch of the left renal artery in the sagittal plane in systole. The RCT:Ao ratio of chronic kidney disease (CKD) patients was 0.50 ± 0.11 (mean ± standard deviation). The RCT:Ao ratio in normal dogs was 0.67 ± 0.07. The RCT:Ao ratio in patients with acute kidney injury (AKI) was 0.83 ± 0.05. There was a statistically significant difference between normal dogs and dogs with CKD (P < 0.001) and between normal dogs and dogs with AKI (P < 0.001). In conclusion, findings from the current study supported using the RCT:Ao ratio as a non-invasive quantitative method for characterizing kidney pathology in dogs with acute or chronic renal disease.

Fungal balls detected using ultrasonography in the urinary bladder of a dog.

A 9-year-old dog was presented with hematuria and urinary incontinence. Ultrasonography revealed multiple mobile echogenic ball-shaped structures without distal acoustic shadowing within the lumen. A cystocentesis was performed and a urinalysis of the urine revealed fungus. Candida albicans was identified using an additional urine culture. The patient was finally diagnosed with fungal cystitis with mobile fungal balls and managed with Itraconazole. Follow-up ultrasonography demonstrated the resolution of cystitis without fungal balls. Our findings suggest that fungal balls should be considered as a differential diagnosis when echogenic mobile ball-shaped structures are identified in the urinary bladder of a diabetic or immunocompromised patient.

Evaluation of urethral thickness using ultrasonography in healthy small-breed dogs.

Introduction: Urethral thickness measurements can be indicative of the pathological state of a patient; however to the best of our knowledge, no measurement reference range has been established in small-breed dogs. This study aimed to establish reference ranges for total urethral thickness and urethral wall thickness in healthy small-breed dogs; "urethral wall thickness" was assumed to be 1/2 of the "total urethral thickness." Methods: Total urethral thickness was measured by ultrasonography in 240 healthy small-breed dogs. In both female and male dogs, the thickness was measured in the mid-sagittal plane. In female dogs, it was measured immediately before the pelvic bone. In male dogs, it was measured caudal to the prostate and cranial to the pelvic bone. The total urethral thickness we measured is the total thickness of the collapsed urethra, which is the sum of the thicknesses of the dorsal and ventral urethral wall. Results: The mean value of total urethral thickness was 3.15 ± 0.83 mm (urethral wall thickness, 1.58 ± 0.41 mm) in 240 small-breed dogs. The total urethral thickness was significantly greater in male dogs than in female dogs (p < 0.001), even when compared among the same breeds (p < 0.05). The mean value of the total urethral thickness in females was 2.78 ± 0.60 mm (urethral wall thickness, 1.39 ± 0.30 mm), and 3.53 ± 0.86 mm (urethral wall thickness, 1.76 ± 0.43 mm) in males. There was very weak positive correlation between body weight (BW) and total urethral thickness (R2 = 0.109; ß = 0.330; p < 0.001). Intraobserver reliability measured by intraclass correlation coefficient (ICC) was 0.986 (p < 0.001) and interobserver reliability measured by ICC was 0.966 (p < 0.001). Discussion: This study described the differences in total urethral thickness between breeds, sexes, and sterilization status, and the correlation between BW and total urethral thickness. Furthermore, this is the first study to provide reference ranges of total urethral thickness and urethral wall thickness in small-breed dogs using ultrasonography, and is expected to be useful for urethral evaluation in veterinary diagnostic imaging.