Detalhe da pesquisa
1.
TOPBPing up DSBs with PARylation.
Mol Cell
; 82(14): 2538-2540, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35868254
2.
TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.
Mol Cell
; 81(12): 2583-2595.e6, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33961797
3.
CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress.
Mol Cell
; 80(3): 410-422.e6, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33108758
4.
Charity begins at home: non-coding RNA functions in DNA repair.
Nat Rev Mol Cell Biol
; 14(3): 181-9, 2013 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23385724
5.
CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.
Nature
; 575(7783): 523-527, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723267
6.
CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining.
Proc Natl Acad Sci U S A
; 119(49): e2214935119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442094
7.
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
Nature
; 563(7732): 522-526, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30464262
8.
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Nature
; 543(7644): 211-216, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28241136
9.
Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome.
Proc Natl Acad Sci U S A
; 117(21): 11409-11420, 2020 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404420
10.
Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours.
Br J Cancer
; 126(7): 1027-1036, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887522
11.
Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks.
Mol Cell
; 54(3): 512-25, 2014 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24703952
12.
MicroRNA profiling in a case-control study of African American women with uterine serous carcinoma.
Gynecol Oncol
; 163(3): 453-458, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607711
13.
Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial.
Lancet Oncol
; 21(7): 957-968, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32553118
14.
Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer.
Carcinogenesis
; 41(7): 904-908, 2020 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32556091
15.
A systemic approach to screening high-throughput RT-qPCR data for a suitable set of reference circulating miRNAs.
BMC Genomics
; 21(1): 111, 2020 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005151
16.
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.
Mol Cell
; 41(2): 210-20, 2011 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21195000
17.
A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
BMC Genomics
; 19(1): 37, 2018 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321003
18.
DNA breaks and chromosome pulverization from errors in mitosis.
Nature
; 482(7383): 53-8, 2012 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22258507
19.
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements.
Mol Cell
; 35(5): 610-25, 2009 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19748357
20.
Distinct phosphatases antagonize the p53 response in different phases of the cell cycle.
Proc Natl Acad Sci U S A
; 111(20): 7313-8, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711418