Detalhe da pesquisa
1.
Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes.
Genome Res
; 32(7): 1328-1342, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162697
2.
Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers.
Genome Res
; 32(7): 1343-1354, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34933939
3.
TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2.
Mol Cancer
; 22(1): 108, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37430263
4.
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.
Blood
; 138(19): 1855-1869, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34125178
5.
De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells.
Mol Cancer
; 21(1): 65, 2022 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35246138
6.
Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia.
Genes Chromosomes Cancer
; 59(4): 261-267, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31677197
7.
SET-NUP214 is a recurrent γδ lineage-specific fusion transcript associated with corticosteroid/chemotherapy resistance in adult T-ALL.
Blood
; 123(12): 1860-3, 2014 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24449214
8.
An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
Haematologica
; 101(6): 732-40, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26944475
9.
PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax.
Clin Cancer Res
; 30(1): 94-105, 2024 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37889114
10.
A conserved transcriptional program for MAIT cells across mammalian evolution.
J Exp Med
; 221(2)2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117256
11.
NAP1L1-MLLT10 is a rare recurrent translocation that is associated with HOXA activation and poor treatment response in T-cell acute lymphoblastic leukaemia.
Br J Haematol
; 174(3): 470-3, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26455581
12.
Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup.
Sci Transl Med
; 13(595)2021 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34039737
13.
A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors.
Cell Mol Immunol
; 18(7): 1662-1676, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34117371
14.
ALK-transformed mature T lymphocytes restore early thymus progenitor features.
J Clin Invest
; 130(12): 6395-6408, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33141118
15.
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.
J Exp Med
; 217(9)2020 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32667968
16.
Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.
Blood Adv
; 3(3): 461-475, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30755435
17.
Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia.
Blood Adv
; 1(12): 733-747, 2017 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29296717
18.
Optical genome mapping refines cytogenetic diagnostics, prognostic stratification and provides new molecular insights in adult MDS/AML patients.
Blood Cancer J
; 12(9): 126, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055992
19.
Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.
J Clin Oncol
; 35(23): 2683-2691, 2017 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28605290
20.
Targeting IRAK1 in T-cell acute lymphoblastic leukemia.
Oncotarget
; 6(22): 18956-65, 2015 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068967