Detalhe da pesquisa
1.
Age-related macular degeneration: A disease of extracellular complement amplification.
Immunol Rev
; 313(1): 279-297, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36223117
2.
Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both chromosomes 1q32 and 10q26.
Proc Natl Acad Sci U S A
; 119(20): e2118510119, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35561216
3.
Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.
Am J Hum Genet
; 108(8): 1385-1400, 2021 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260948
4.
Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.
Am J Hum Genet
; 108(8): 1367-1384, 2021 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260947
5.
Theranos's lesson for investors: speak to lab workers.
Nature
; 601(7894): 508, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35079153
6.
The complement system in age-related macular degeneration.
Cell Mol Life Sci
; 78(10): 4487-4505, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33751148
7.
CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-κB Pathway.
Int J Mol Sci
; 22(16)2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445430
8.
Association of plasma trace element levels with neovascular age-related macular degeneration.
Exp Eye Res
; 201: 108324, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33098886
9.
Loss-of-Function Mutations in the CFH Gene Affecting Alternatively Encoded Factor H-like 1 Protein Cause Dominant Early-Onset Macular Drusen.
Ophthalmology
; 126(10): 1410-1421, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905644
10.
Complement factor H in host defense and immune evasion.
Cell Mol Life Sci
; 74(9): 1605-1624, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27942748
11.
Age-related macular degeneration: genome-wide association studies to translation.
Genet Med
; 18(4): 283-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020418
12.
Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.
J Immunol
; 193(10): 4962-70, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25305316
13.
Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions.
J Immunol
; 190(5): 2049-57, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23365078
14.
Investing in vision: Innovation in retinal therapeutics and the influence on venture capital investment.
Prog Retin Eye Res
; 99: 101243, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38218527
15.
The impact of substrate stiffness on morphological, transcriptional and functional aspects in RPE.
Sci Rep
; 14(1): 7488, 2024 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38553490
16.
Structural basis for complement factor H linked age-related macular degeneration.
J Exp Med
; 204(10): 2277-83, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17893204
17.
Therapeutic targeting of the complement system in ocular disease.
Drug Discov Today
; 28(11): 103757, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657753
18.
Extra-viral DNA in adeno-associated viral vector preparations induces TLR9-dependent innate immune responses in human plasmacytoid dendritic cells.
Sci Rep
; 13(1): 1890, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732401
19.
Delivery Systems in Ocular Retinopathies: The Promising Future of Intravitreal Hydrogels as Sustained-Release Scaffolds.
Pharmaceutics
; 15(5)2023 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242726
20.
10q26 - The enigma in age-related macular degeneration.
Prog Retin Eye Res
; 96: 101154, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36513584